Results 71 to 80 of about 16,055 (293)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
On the perfectness of C^{∞,s}-diffeomorphism groups on a foliated manifold [PDF]
Opuscula Mathematica, 2008 The notion of \(C^{r,s}\) and \(C^{\infty,s}\)-diffeomorphisms is introduced. It is shown that the identity component of the group of leaf preserving \(C^{\infty,s}\)-diffeomorphisms with compact supports is perfect.
Jacek Lech
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Homotopy invariance of cohomology and signature of a riemannian foliation [PDF]
, 2017 We prove that any smooth foliation that admits a Riemannian foliation structure has a well-defined basic signature, and this geometrically defined invariant is actually a foliated homotopy invariant.
Richardson, Ken, Habib, Georges
core +1 more source
Bulletin of the Mineral Research and Exploration, 2019 Yeşilöz Makaslama Zonu (YMZ), Alanya bölgesinde yer alan Alanya Nap Kompleksi’nin, Mahmutlar alt napı içerisinde belirlenmiş büyük bir makaslama zonudur.
Volkan ÖZAKSOY
doaj +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
, 2018 © 2018, Fondazione Annali di Matematica Pura ed Applicata and Springer-Verlag GmbH Germany, part of Springer Nature. This document is the Published Manuscript, version of a Published Work that appeared in final form in Annali di Matematica Pura ed ...
Alves, Benigno O. +2 more
core +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
FEBS Open Bio, EarlyView.In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
A Lipschitz condition along a transversal foliation implies local uniqueness for ODEs
Electronic Journal of Qualitative Theory of Differential Equations, 2018 We prove the following result: if a continuous vector field $F$ is Lipschitz when restricted to the hypersurfaces determined by a suitable foliation and a transversal condition is satisfied at the initial condition, then $F$ determines a locally unique ...
José Ángel Cid, F. Adrián Tojo
doaj +1 more source