Results 141 to 150 of about 38,858 (259)

Falling Use of Preconception Folic Acid Supplements and Neural Tube Defect Prevention

open access: yes
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Danielle Schoenaker   +4 more
wiley   +1 more source

What Endocrinologists Should Know About Iodine: Population Deficiency, Individual Excess and Misinformation in the United Kingdom

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Iodine deficiency, once considered eliminated in the United Kingdom, has re‐emerged, particularly among women of reproductive age, in whom requirements are increased during pregnancy and lactation. The declining consumption of dairy and white fish, the emerging use of unfortified plant‐based milk alternatives, and the absence of a national ...
Peter N. Taylor   +11 more
wiley   +1 more source

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman   +15 more
wiley   +1 more source

Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland

open access: yesDiabetic Medicine, EarlyView.
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney   +14 more
wiley   +1 more source

Altered GNAS imprinting due to folic acid deficiency contributes to poor embryo development and may lead to neural tube defects. [PDF]

open access: yesOncotarget, 2017
Wang L   +12 more
europepmc   +1 more source

Association between gestational diabetes, ethnicity and migrant length of residence: An Australian cohort study

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Investigate the relationship of gestational diabetes (GDM) risk for specific migrant groups compared to the Australian born of each ethnic group and length of residence (LOR) in Australia. Methods Retrospective observational cohort study from June 2020 to November 2023 at 10 Australian hospitals.
Sheila Pham   +12 more
wiley   +1 more source

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

open access: yesThe FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet   +6 more
wiley   +1 more source

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