Results 71 to 80 of about 251,175 (335)

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20–75 Years of Age

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek, Lauren Jenner, Abigail L. Hogan, Laura Friedman, Elizabeth Berry‐Kravis, Flora Tassone, Tatyana Adayev, Amanda J. Fairchild, Jane E. Roberts   +8 more
wiley   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei, Chunliu Huang, Zenghua Zhou, Yanni Lan   +3 more
wiley   +1 more source

Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer

Journal of Biological Chemistry, 2014
Background: A carbohydrate of follicle-stimulating hormone (FSH) has been proposed to sterically block other FSH molecules from binding to the putative receptor (FSHR) trimer.
Xuliang Jiang, David J Fischer, Xiaoyan Chen, S. Mckenna, Heli Liu, V. Sriraman, Henry N. Yu, A. Goutopoulos, S. Arkinstall, Xiaolin He   +9 more
semanticscholar   +1 more source

Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor, Safiya Al Yazeedi, Janaeya Zuri Baher, Chung Cheung, Don D. Sin, Emmanuel Twumasi Osei   +5 more
wiley   +1 more source

Acupuncture for hormonal readiness and gut microbiota in obese polycystic ovary syndrome: an open-label, randomized controlled trial

Frontiers in Endocrinology
ObjectiveTo explore whether acupuncture combined with clomiphene can reduce the luteinizing hormone-to follicle-stimulating hormone ratio and impact the gut microbiota in patients with obese polycystic ovary syndrome.MethodsThis open-label, randomized ...
Tianyu Wu, Guixing Xu, Guixing Xu, Guixing Xu, Xiaojuan Hong, Xiaojuan Hong, Huaying Fan, Jiuzhi Zeng, Yu Liu, Jinqun Hu, Fanrong Liang, Fanrong Liang, Jie Yang, Jie Yang, Jiao Chen, Jiao Chen   +15 more
doaj   +1 more source

The enigma of the gonadotropin-releasing hormone pulse frequency governing individual secretion of luteinizing hormone and follicle-stimulating hormone

F&S Reports, 2023
Luteinizing hormone and follicle-stimulating hormone are the two gonadotropic pituitary hormones stimulated by one hypothalamic gonadotropin-releasing hormone (GnRH) in a pulsatile way.
Cornelis B. Lambalk, M.D., Ph.D.
doaj  

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Data on Western blot and ELISA analysis of medaka (Oryzias latipes) follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) using recombinant proteins expressed with Pichia pastoris

Data in Brief, 2019
The gonadotropins follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) play essential roles in vertebrate reproduction. This article presents data on molecular weight validation of recombinant medaka (Oryzias latipes) (md) gonadotropins Fshβ ...
Susann Burow, Romain Fontaine, Kristine von Krogh, Ian Mayer, Rasoul Nourizadeh-Lillabadi, Lian Hollander-Cohen, Yaron Cohen, Michal Shpilman, Berta Levavi-Sivan, Finn-Arne Weltzien   +9 more
doaj  

Naturally Occurring Follicle-Stimulating Hormone Glycosylation Variants

Journal of Glycomics & Lipidomics, 2014
Follicle-stimulating hormone (FSH) is a member of the glycoprotein hormone family, which is a subfamily of the cystine knot growth factor superfamily [1,2]. The glycoprotein hormones are composed of heterodimeric glycoprotein subunits, a common α-subunit,
John S. Davis, T. Kumar, J. V. May, G. Bousfield   +3 more
semanticscholar   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source