Results 11 to 20 of about 408,258 (430)
Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer [PDF]
, 2013 The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte. Here we show that the different follicular sizes can be explained with diffusion-based limitations on the thickness of the ...
Bächler, M. +3 more
arxiv +3 more sources
Multi-scale modeling of follicular ovulation as a reachability problem [PDF]
Multiscale Modeling & Simulation 6, 3 (2007) 895--912, 2006 During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called atresia. We have designed a multi-scale mathematical model where ovulation and atresia result from a hormonal controlled selection process.
Frederique Clément +4 more
arxiv +7 more sources
Bridging Time Scales in Cellular Decision Making with a Stochastic Bistable Switch [PDF]
arXiv, 2010 Cellular transformations which involve a significant phenotypical change of the cell's state use bistable biochemical switches as underlying decision systems. In this work, we aim at linking cellular decisions taking place on a time scale of years to decades with the biochemical dynamics in signal transduction and gene regulation, occuring on a time ...
A Gougeon +44 more
arxiv +7 more sources
Combined Effect of Follicle–Follicle Interactions and Declining Follicle-Stimulating Hormone on Murine Follicle Health In Vitro1 [PDF]
Biology of Reproduction, 2001 Follicle selection occurs throughout an adult female's reproductive life, with selected, dominant follicle(s) developing to the preovulatory stage whereas the remaining, subordinate follicles within the growing cohort instead undergo atresia and die. To date, most research into follicle dominance has concentrated on its endocrine regulation, although ...
Rebecca Lapping +3 more
openaire +3 more sources
Influence of human chorionic gonadotrophin during ovarian stimulation: an overview
Reproductive Biology and Endocrinology, 2020 It is widely known that luteinising hormone (LH) and human chorionic gonadotrophin (hCG) are integral in the female reproductive lifecycle. Due to the common binding site and similarity in molecular structure, they were previously thought to have ...
Johan Smitz, Peter Platteau
doaj +1 more source
Journal of Education, Health and Sport, 2021 In the following article specific hystochemical features of the fetal ovaries’ structure from mothers with the physiological pregnancy are considered. All fetals were divided into subgroups by taking into consideration the term of gestation, as well as ...
V. O. Poliasnyi, L. S. Kupriianova
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance This paper improves knowledge of the somatic and germ cells of the developing mouse ovary that assemble into ovarian follicles, by determining cellular gene expression, and tracing lineage relationships.
Wanbao Niu, A. Spradling
semanticscholar +1 more source
The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice
Frontiers in Cell and Developmental Biology, 2021 Ovarian aging is a natural process characterized by follicular depletion and a reduction in oocyte quality, resulting in loss of ovarian function, cycle irregularity and eventually infertility and menopause.
Carolina Lliberos +3 more
doaj +1 more source
Hair Follicle Pigmentation [PDF]
Journal of Investigative Dermatology, 2005 Hair shaft melanin components (eu- or/and pheomelanin) are a long-lived record of precise interactions in the hair follicle pigmentary unit, e.g., between follicular melanocytes, keratinocytes, and dermal papilla fibroblasts. Follicular melanogenesis (FM) involves sequentially the melanogenic activity of follicular melanocytes, the transfer of melanin ...
Ralf Paus +6 more
openaire +3 more sources
Apoptosis in the Hair Follicle [PDF]
Journal of Investigative Dermatology, 2006 Apoptosis plays an important role in many physiological processes, ranging from morphogenetic events to adult tissue homeostasis, and defects in its regulation contribute to many disorders. Here we review molecular mechanisms of apoptosis in the hair follicle (HF), whose cyclical growth pattern is repeatedly interrupted by apoptosis-driven involution ...
Douglas Shander +2 more
openaire +2 more sources