Results 41 to 50 of about 266,076 (313)

Effects of insulin-like growth factor-1 on the mRNA expression of estradiol receptors, steroidogenic enzymes, and steroid production in bovine follicles

open access: yesThe Journal of Reproduction and Development, 2023
Insulin-like growth factor-1 (IGF-1) plays a crucial role in follicular growth and stimulates steroid hormone production in bovine follicles. Steroid hormones are synthesized through the actions of steroidogenic enzymes, specifically STAR, CYP11A1, HSD3B,
Ahmad Farid RAWAN   +5 more
doaj   +1 more source

Oocyte maturation in the toad Rhinella arenarum (Amphibia, Anura): Evidence of cAMP involvement in steroid production and action [PDF]

open access: yes, 2018
In this work, we describe the participation of the adenylate cyclase/3′-5′-cyclic adenonsine monophosphate (cAMP) pathway in the seasonal follicular secretion of progesterone (P 4 ) and testosterone (T), and its relationship with the maturation of ...
Arias Torres   +48 more
core   +1 more source

Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]

open access: yes, 2001
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S.   +2 more
core   +1 more source

Hair follicle proteoglycans

open access: yesJournal of Investigative Dermatology, 1993
Proteoglycans are polymorphic macromolecules present in all mammalian tissues, including the skin and its appendages. They consist of a core protein to which one or more glycosaminoglycan chains are covalently attached. Broadly, they can be divided into classes based on location and core protein structure.
openaire   +2 more sources

Steroid profile of porcine follicular fluid and blood serum: Relation with follicular development

open access: yesPhysiological Reports, 2019
The aim of this study was to identify follicular fluid (FF) steroids which reflect follicular development in the early stages of the follicular phase and to establish whether the levels of these FF steroids correspond to their levels in serum.
Natasja G. J. Costermans   +6 more
doaj   +1 more source

Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise [PDF]

open access: yes, 2011
The mechanism of chemotherapy-induced acceleration of ovarian aging is not fully understood. We used doxorubicin, a widely used cancer chemotherapeutic, in a variety of in vivo xenograft, and in vitro models to investigate the impact of chemotherapy ...
Darzynkiewicz, Zbigniew   +3 more
core   +1 more source

Technologies for the Production of Fertilizable Mammalian Oocytes

open access: yesApplied Sciences, 2019
Women affected by ovarian pathologies or with cancer can usually preserve fertility by egg/embryo freezing. When oocyte retrieval is not feasible, the only option available is ovarian tissue cryopreservation and transplantation.
Gianna Rossi   +6 more
doaj   +1 more source

Stepped vitrification technique for human ovarian tissue cryopreservation [PDF]

open access: yes, 2019
The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation.
Amorin, C.A.   +9 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Changes in Ovarian Activity and Expressions of Follicle Development Regulation Factors During the Laying–Incubation Cycle in Magang Geese

open access: yesAnimals
Strong broodiness is an important reproductive characteristic of Magang geese, manifested by periodic laying–incubation activities during the breeding season.
Rui Wu   +8 more
doaj   +1 more source

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