Results 1 to 10 of about 44,722 (116)

Regenerative potential of CD200- subpopulations of hair follicle bulge [PDF]

Frontiers in Cell and Developmental Biology
The hair follicle bulge is regarded as a reservoir of epithelial stem cells for hair regeneration. Hair follicle bulge cells are generally characterized by CD200 expression.
Ting Sun, Ting Sun, Sayuri Hamano, Jing Chen, Lichen Ling, Jinran Lin, Lei Yan, Lei Yan, Tatsuto Kageyama, Tatsuto Kageyama, Fuyue Wu, Zheng Lin Tan, Wenyu Wu, Junji Fukuda, Junji Fukuda   +14 more
doaj   +2 more sources

Early Compound Nutritional Intervention Improves Hair Follicle Development in Northwest Xizang White Cashmere Goats: An Analysis Based on Skin Multi-Omics [PDF]

Animals
The Northwest Xizang White Cashmere goat has a high global reputation for good goat cashmere germplasm characteristics, and its cashmere industry is the economic pillar of the herdsmen in the northwest plateau of Xizang.
Yiming Liu, Xiaolong Wu, Jiaoyang A, Zepeng Duan, Meng Yao, Siying Meng, Hui Zhao, Jie Liu, Yunxia Guo, Zili Ren, Yujiang Wu, Yueqin Liu, Hongna Wang   +12 more
doaj   +2 more sources

Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies

Cells
With alopecia affecting millions globally, recent advancements in the understanding of hair follicle biology have driven the development of novel therapies focused on hair regrowth. This review discusses two emerging therapeutic strategies: hair follicle
Lindsey Bordone, Mateen Motavaf, Apoorva Mehta   +2 more
exaly   +3 more sources

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]

PLoS ONE, 2012
Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang, Xuming Zhu, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo, Gang Ma   +7 more
doaj   +1 more source

Hair Graying Regulators Beyond Hair Follicle

Frontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen, Jing Chen, Yixin Zheng, Chen Hu, Xuexiao Jin, Xiaoping Chen, Ying Xiao, Chaochen Wang, Chaochen Wang   +8 more
doaj   +1 more source

Gene network analysis reveals candidate genes related with the hair follicle development in sheep

BMC Genomics, 2022
Background Merino sheep are the most famous fine wool sheep in the world. They have high wool production and excellent wool quality and have attracted worldwide attention. The fleece of the Merino sheep is composed predominantly of wool fibers grown from
Junmin He, Bingru Zhao, Xixia Huang, Xuefeng Fu, Guifen Liu, Yuezhen Tian, Cuiling Wu, Jingyi Mao, Jing Liu, Shuangbao Gun, Kechuan Tian   +10 more
doaj   +1 more source

Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits

Biology, 2023
Hair follicle development directly affects the development of the rabbit fur industry. The growth and development of a hair follicle is modified and regulated by many genes and mechanisms. M6A is an important RNA modification.
Gang Luo, Ruiguang Gong, Yaotian Ai, Tongyan Zhu, Zhanjun Ren   +4 more
doaj   +1 more source

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

Cells, 2020
Studies in humans and mice have revealed that hair follicle morphogenesis relies on tightly coordinated ectodermal–mesodermal interactions, involving multiple signals and regulatory factors.
Shanhe Wang, Fang Li, Jinwang Liu, Yuelang Zhang, Yujie Zheng, Wei Ge, Lei Qu, Xin Wang   +7 more
doaj   +1 more source

Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

Asian Journal of Pharmaceutical Sciences, 2022
The hair follicle is not only a critical penetration route in percutaneous absorption but also has been recognized to be a target for hair follicle-associated disorders, such as androgenetic alopecia (AGA) and acne vulgaris.
Yueting Gu, Qiong Bian, Yanjun Zhou, Qiaoling Huang, Jianqing Gao   +4 more
doaj   +1 more source

Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which is key to hair regeneration. However, it is not clear whether recombinant
Chen Yijun, Lu Zhujin, Feng Jiaxin, Chen Zefeng, Liu Zejian, Wang Xiuqi, Yan Huichao, Gao Chunqi   +7 more
doaj   +1 more source