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Hair Graying Regulators Beyond Hair Follicle [PDF]

open access: yesFrontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen   +8 more
doaj   +3 more sources

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]

open access: yesPLoS ONE, 2012
Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang   +7 more
doaj   +1 more source

Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits

open access: yesBiology, 2023
Hair follicle development directly affects the development of the rabbit fur industry. The growth and development of a hair follicle is modified and regulated by many genes and mechanisms. M6A is an important RNA modification.
Gang Luo   +4 more
doaj   +1 more source

Gene network analysis reveals candidate genes related with the hair follicle development in sheep

open access: yesBMC Genomics, 2022
Background Merino sheep are the most famous fine wool sheep in the world. They have high wool production and excellent wool quality and have attracted worldwide attention. The fleece of the Merino sheep is composed predominantly of wool fibers grown from
Junmin He   +10 more
doaj   +1 more source

Bioengineering the Hair Follicle [PDF]

open access: yesOrganogenesis, 2007
The hair follicle develops from the primitive embryonic epidermis as a result of complex epithelial-mesenchymal interactions. The full follicle, consisting of epithelial cylinders under control of a proximal lying mesenchymal papilla, grows in cycles giving rise to a new hair shaft during each cycle.
K, Stenn   +5 more
openaire   +2 more sources

Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

open access: yesAsian Journal of Pharmaceutical Sciences, 2022
The hair follicle is not only a critical penetration route in percutaneous absorption but also has been recognized to be a target for hair follicle-associated disorders, such as androgenetic alopecia (AGA) and acne vulgaris.
Yueting Gu   +4 more
doaj   +1 more source

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

open access: yesCells, 2020
Studies in humans and mice have revealed that hair follicle morphogenesis relies on tightly coordinated ectodermal–mesodermal interactions, involving multiple signals and regulatory factors.
Shanhe Wang   +7 more
doaj   +1 more source

Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway

open access: yesActa Biochimica et Biophysica Sinica, 2023
Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which is key to hair regeneration. However, it is not clear whether recombinant
Chen Yijun   +7 more
doaj   +1 more source

Hair Follicle Pigmentation [PDF]

open access: yesJournal of Investigative Dermatology, 2005
Hair shaft melanin components (eu- or/and pheomelanin) are a long-lived record of precise interactions in the hair follicle pigmentary unit, e.g., between follicular melanocytes, keratinocytes, and dermal papilla fibroblasts. Follicular melanogenesis (FM) involves sequentially the melanogenic activity of follicular melanocytes, the transfer of melanin ...
Slominski, Andrzej   +5 more
openaire   +2 more sources

Hair Follicle Nevus [PDF]

open access: yesDermatology, 2009
We present a case of hair follicle nevus, a rare hamartoma composed of vellus hair follicles. Hair follicle nevus should be differentiated from accessory auricle, trichofolliculoma and hair nevus.
A, Komura, M, Tani
openaire   +2 more sources

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