Results 11 to 20 of about 282,949 (249)

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S., Iain S Haslam, Jonathan A Hardman, Hardman, Jonathan A, Bessam Farjo (714627), Farjo, Bessam, Nilofer Farjo (714626), Nilofer Farjo, Jonathan A. Hardman (714625), Ralf Paus, Farjo, Nilofer, Bessam Farjo, Iain S. Haslam (452871), Haslam, Iain S, Hardman, Jonathan A., Paus, Ralf, Ralf Paus (261703)   +16 more
core   +5 more sources

Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]

, 2003
The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Todd, A.J., Riddell, J.S., Scott, D.T., Hughes, D.I.   +3 more
core   +8 more sources

Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling

BMC Genomics, 2020
Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment.
Ruoyang Zhao, Wu Yihan, Yiping Zhao, Bei Li, Haige Han, Togtokh Mongke, Tugeqin Bao, Wenxing Wang, Manglai Dugarjaviin, Dongyi Bai   +9 more
doaj   +1 more source

Single-Cell Profiling Reveals a Protective WNT5A-ATF3-FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia. [PDF]

Adv Sci (Weinh)
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Luo R, Fang K, Zhao C, Xiong J, Zhu Y, Lu M, Yan H, Li Z, Wu B, Jiang H, Li Y.   +10 more
europepmc   +2 more sources

Prolactin delays hair regrowth in mice [PDF]

, 2006
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G., Nixon, A.J., Pearson, A.J., Ormandy, C.J., Blazek, K., Wilkins, Richard J., Craven, A.J.   +6 more
core   +1 more source

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

Scientific Reports, 2022
Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing.
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita   +9 more
doaj   +1 more source

Advances in Understanding Hair Growth [version 1; referees: 2 approved]

F1000Research, 2016
In this short review, I introduce an integrated vision of human hair follicle behavior and describe opposing influences that control hair follicle homeostasis, from morphogenesis to hair cycling.
Bruno A. Bernard
doaj   +1 more source

Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications

Frontiers in Immunology, 2022
Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder affecting growing hair follicles in susceptible individuals, which results in a non-scarring and reversible hair loss with a highly unpredictable course.
Shahnawaz D. Jadeja, Desmond J. Tobin, Desmond J. Tobin   +2 more
doaj   +1 more source

Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems [PDF]

, 2007
PhDEmbryonic development is regulated by a number of signalling pathways, Which are critical for normal growth. Many of these genes then continue to play an important role in the regulation of cell growth and differentiation in adult.
Ikram, Mohammed S, Ikram, Mohammed. S.
core   +4 more sources

Expression profile of long non-coding RNA in inner Mongolian cashmere goat with putative roles in hair follicles development

Frontiers in Veterinary Science, 2022
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma, Fangzheng Shang, Youjun Rong, Jianfeng Pan, Min Wang, Shuran Niu, Yunpeng Qi, Yanbo Li, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +18 more
doaj   +1 more source