Results 31 to 40 of about 168,824 (316)

Effects of insulin-like growth factor-1 on the mRNA expression of estradiol receptors, steroidogenic enzymes, and steroid production in bovine follicles

The Journal of Reproduction and Development, 2023
Insulin-like growth factor-1 (IGF-1) plays a crucial role in follicular growth and stimulates steroid hormone production in bovine follicles. Steroid hormones are synthesized through the actions of steroidogenic enzymes, specifically STAR, CYP11A1, HSD3B,
Ahmad Farid RAWAN, Hikmatullah LANGAR, Maho MUNETOMO, Yuki YAMAMOTO, Kohei KAWANO, Koji KIMURA   +5 more
doaj   +1 more source

Steroid profile of porcine follicular fluid and blood serum: Relation with follicular development

Physiological Reports, 2019
The aim of this study was to identify follicular fluid (FF) steroids which reflect follicular development in the early stages of the follicular phase and to establish whether the levels of these FF steroids correspond to their levels in serum.
Natasja G. J. Costermans, Nicoline M. Soede, Marco Blokland, Frederike vanTricht, Jaap Keijer, Bas Kemp, Katja J. Teerds   +6 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Changes in Ovarian Activity and Expressions of Follicle Development Regulation Factors During the Laying–Incubation Cycle in Magang Geese

Animals
Strong broodiness is an important reproductive characteristic of Magang geese, manifested by periodic laying–incubation activities during the breeding season.
Rui Wu, Junfeng Sun, Jianqiu Pan, Xu Shen, Danli Jiang, Hongjia Ouyang, Danning Xu, Yunbo Tian, Yunmao Huang   +8 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Effects of physiological oxygen tension on human cumulus-oocyte-complex metabolism during in vitro maturation: an exploratory study

Journal of Ovarian Research
In vitro oocyte maturation (IVM) is an internationally recognized, patient-friendly assisted reproductive technology, particularly valuable for women with polycystic ovary syndrome (PCOS).
Ellen Anckaert, Gamze Ates, Arjen Liveyns, Heidi Van Ranst, Linde Mostinckx, Wilfried Cools, Anneleen Mortier, Ann Massie, Michel De Vos, Nazli Akin   +9 more
doaj   +1 more source

Technologies for the Production of Fertilizable Mammalian Oocytes

Applied Sciences, 2019
Women affected by ovarian pathologies or with cancer can usually preserve fertility by egg/embryo freezing. When oocyte retrieval is not feasible, the only option available is ovarian tissue cryopreservation and transplantation.
Gianna Rossi, Valentina Di Nisio, Guido Macchiarelli, Stefania Annarita Nottola, Iman Halvaei, Lucia De Santis, Sandra Cecconi   +6 more
doaj   +1 more source

HIV-1 infected humanized DRAGA mice develop HIV-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues

Frontiers in Immunology, 2022
A major barrier in the use of humanized mice as models of HIV-1 (HIV) infection is the inadequate generation of virus-specific antibody responses. Humanized DRAGA (hDRAGA) mice generate antigen-specific class switched antibodies to several pathogens, but
Matthew T. Ollerton, Joy M. Folkvord, Kristina K. Peachman, Soumya Shashikumar, Elaine B. Morrison, Linda L. Jagodzinski, Sheila A. Peel, Mohammad Khreiss, Richard T. D’Aquila, Sofia Casares, Mangala Rao, Elizabeth Connick   +11 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Expression of Relaxin Family Peptide Receptors 1 and 3 in the Ovarian Follicle of Japanese Quail

The Journal of Poultry Science
In our previous studies, we demonstrated that the primary source of relaxin 3 (RLN3) in Japanese quail is ovarian granulosa cells. Although several relaxin family peptide (RXFP) receptors have been sequenced, the intricacies of these receptors in avian ...
Khoi X. Hoang, Mei Matsuzaki, Tetsuya Kohsaka, Tomohiro Sasanami   +3 more
doaj   +1 more source