Results 1 to 10 of about 2,731 (100)
Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): To evaluate the effects of Amburana cearensis leaf extract against cisplatin-induced ovarian toxicity in mice and involvement of p-PTEN and p-Akt proteins. Materials and Methods: A.
Bruna B. Gouveia +10 more
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Animals, 2023 In this study, we aimed to better understand the difference between the functions of the two types of granulosa cells and sought to discover more key genes involved in follicle development and follicle selection.
Xubin Du +7 more
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Ovarian Biomechanics: From Health to Disease
Frontiers in Oncology, 2022 Biomechanics is a physical phenomenon which mainly related with deformation and movement of life forms. As a mechanical signal, it participates in the growth and development of many tissues and organs, including ovary.
Chenchen Sun +4 more
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Regulation of SIRT1 in Ovarian Function: PCOS Treatment
Current Issues in Molecular Biology, 2023 The sirtuin family, a group of NAD+-dependent class 3 histone deacetylases (HDACs), was extensively studied initially as a group of longevity genes that are activated in caloric restriction and act in concert with nicotinamide adenine dinucleotides to ...
Xinrong Li +13 more
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Cells, 2022 How progesterone influences ovarian follicle growth is a difficult question to answer because ovarian cells synthesize progesterone and express not only the classic nuclear progesterone receptor but also members of the progestin and adipoQ receptor ...
John J. Peluso
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Disordered follicle development [PDF]
Molecular and Cellular Endocrinology, 2013 Alterations of ovarian follicle morphology and function have been well documented in women with PCOS. These include increased numbers of growing preantral follicles, failure of follicle growth beyond the mid-antral stage, evidence of granulosa call degeneration, and theca cell hyperplasia.
R Jeffrey, Chang, Heidi, Cook-Andersen
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Frontiers in Veterinary Science, 2023 The reproductive tract is susceptible to infection by a variety of bacteria, which can impair ovarian and uterine function. However, there is little known about whether mild infection can harm follicle development and embryo implantation.
Yazhuo Du +10 more
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New insight into the role of macrophages in ovarian function and ovarian aging
Frontiers in Endocrinology, 2023 Macrophages (MΦs) are the most abundant leukocytes in mammalian ovaries that have heterogeneity and plasticity. A body of evidence has indicated that these cells are important in maintaining ovarian homeostasis and they play critical roles in ovarian ...
Maoxing Tang, Manzhi Zhao, Yuhua Shi
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Ovarian Follicle Development Requires Smad3 [PDF]
Molecular Endocrinology, 2004 AbstractSmad3 is an important mediator of the TGFβ signaling pathway. Interestingly, Smad3-deficient (Smad3−/−) mice have reduced fertility compared with wild-type (WT) mice. To better understand the molecular mechanisms underlying the reduced fertility in Smad3−/− animals, this work tested the hypothesis that Smad3 deficiency interferes with three ...
Dragana, Tomic +5 more
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Biology and Biotechnology of Follicle Development [PDF]
The Scientific World Journal, 2012 Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the ...
G.A. Palma +5 more
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