Results 221 to 230 of about 60,626 (311)

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng   +3 more
wiley   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

open access: yesCancer Science, EarlyView.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou   +5 more
wiley   +1 more source

Proneurogenic actions of follicle-stimulating hormone on neurospheres derived from ovarian cortical cells in vitro. [PDF]

open access: yesBMC Vet Res
González-Gil A   +8 more
europepmc   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele   +9 more
wiley   +1 more source

The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men. [PDF]

open access: yesNutr Diabetes
Bin DH   +9 more
europepmc   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan   +14 more
wiley   +1 more source

Association of the Effect of Alcohol Consumption on Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), and Testosterone Hormones in Men: A Systematic Review and Meta-Analysis. [PDF]

open access: yesInt J Prev Med
Moosazadeh M   +10 more
europepmc   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak   +4 more
wiley   +1 more source

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