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Bioassays of Follicle Stimulating Hormone

Endocrine Reviews, 1988
With the availability of these highly sensitive in vitro assays, measurement of bio-FSH in serum and urine becomes possible. Clinical studies have been done to investigate the role of bioactive FSH in different physiological and pathological conditions. There are however problems with these assays.
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Feedback of Follicle-Stimulating Hormone to Inhibit Luteinizing Hormone and Stimulate Follicle-Stimulating Hormone Release in Ovariectomized Rats

Neuroendocrinology, 2008
Injection of ovine follicle-stimulating hormone (o-FSH) into the third cerebral ventricle significantly suppressed plasma luteinizing hormone (LH) release in conscious, unrestrained ovariectomized rats. Intraventricular injection of o-FSH (0.5 µg) significantly lowered the plasma levels of LH by 70 min and decreased pulse frequency, whereas the ...
W H, Yu, S M, McCann
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Follicle-Stimulating Hormone

2013
About 15 % of all couples experience infertility at some time during their reproductive lives. Nowadays, infertility can be treated by the use of assisted reproductive technologies (ART), such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Tom Sam   +3 more
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Purification and Characterization of Bovine Follicle-Stimulating Hormone: Comparison with Ovine Follicle-Stimulating Hormone*

Endocrinology, 1979
Highly purified FSH was obtained from several batches of bovine pituitaries by sequential application of the following procedures: 1) extraction with an alcoholic sodium acetate buffer, 2) fractionation with metaphosphoric acid, 3) fractionation with ammonium sulfate, 4) gel filtration on Sephadex G-150, 5) ion exchange chromatography on CM-Sephadex, 6)
H J, Grimek, J, Gorski, B C, Wentworth
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Role of follicle-stimulating hormone receptor Ser680Asn polymorphism in the efficacy of follicle-stimulating hormone

Fertility and Sterility, 2003
To evaluate the association between FSH efficacy and FSHR alleles.Retrospective study.University-based fertility unit and a private center for biomedical research.One hundred two women with ovarian function who were undergoing controlled ovarian stimulation (COS).
Francisco, de Castro   +6 more
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Follicle-Stimulating Hormone and Advanced Follicle Development in the Human

Archives of Medical Research, 2001
The great majority of human oocytes is destined to undergo atresia. Only follicles able to respond to stimulation by follicle-stimulating hormone (FSH) will enter the final stage of development and ovulate. While the role of FSH in early follicle development is unclear, late follicular development is FSH-dependent.
N S, Macklon, B C, Fauser
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ORAL CONTRACEPTIVES AND FOLLICLE-STIMULATING HORMONE

The Lancet, 1968
The authors report the effects of an oral contraceptive on plasma levels of follicle-stimulating-hormone (FSH) as measured by a double-antibody method of radioimmunoassay. Reichert 780 pituitary FSH labelled with iodine-131 and rabbit antihuman FSH serum were used with the International Reference Preparation number 2 of human menopausal gonadotrophin ...
H, Schmidt-Elmendorff, H, Kopera
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Follicle stimulating hormone as a predictor of fertility

Current Opinion in Obstetrics and Gynaecology, 1998
Tests for diminished ovarian reserve provide valuable prognostic information for women considering assisted reproductive technology. The best characterized screening tool for a general infertility patient is the clomiphene citrate challenge test. These screening tests do not have absolute sensitivity or specificity.
K, Barnhart, J, Osheroff
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Regulation of Follicle-Stimulating Hormone Receptor

Hormone Research, 2008
The acquisition of follicle-stimulating hormone (FSH) receptors during folliculogenesis is believed to be a key event in follicle development. We have examined the effects of FSH and activin on FSH receptor mRNA in cultured rat granulosa cells. Treatment of granulosa cells with FSH resulted in transient suppression of the FSH receptor mRNA levels 2-6 h
T, Minegishi   +9 more
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Immunology of Follicle-Stimulating Hormone and Luteinizing Hormone

1970
Publisher Summary This chapter discusses immunology of follicle-stimulating hormone and luteinizing hormone. Although great strides have been made in the last few years due to the introduction of modern physiochemical techniques, absolute purity of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has not yet been attained.
B, Lunenfeld, A, Eshkol
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