Results 1 to 10 of about 27,853 (255)

Gonadotropins and Ovarian Cancer [PDF]

Endocrine Reviews, 2007
Ovarian epithelial cancer (OEC) accounts for 90% of all ovarian cancers and is the leading cause of death from gynecological cancers in North America and Europe. Despite its clinical significance, the factors that regulate the development and progression of ovarian cancer are among the least understood of all major human malignancies.
Jung-Hye Choi, Wong Ast, Peter C K Leung   +2 more
exaly   +6 more sources

Gonadotropins beyond ART [PDF]

, 2017
Gonadotropins (LH, FSH and hCG) play a central role in controlling steroidogenesis and gametogenesis. For this reason, they are largely used in the treatment of infertility, especially in the setting of assisted reproductive technique.
Livio Casarini, Simoni Manuela, Giulia Brigante, Sara De Vincentis   +3 more
core   +1 more source

Chorionic gonadotropin [PDF]

Cancer, 1976
One of the most exciting and useful developments in modern oncology has been the recognition that certain biochemical tags can be used as cell markers in diagnosis, in monitoring the effects of anti-tumor therapy, and in follow-up to detect tumor recurrence. The measurement of chorionic gonadotropin (CG) in women with choriocarcinoma and/or gestational
openaire   +2 more sources

Pituitary gonadotropins and autoimmunity

, 2014
Autoimmune disease occurs when the body produces an inappropriate immune response against its own tissues producing antibodies, called autoantibodies, reacting to specific antigens.
BRANCIA, CARLA, COCCO, CRISTINA, NOLI, BARBARA, D'AMATO, FILOMENA   +3 more
core   +1 more source

Gonadotropins in insects: An overview

, 2001
Control of gonad development in insects requires juvenile hormone, ecdysteroids, and a peptidic brain gonadotropin(s). Compared to vertebrates, the situation in insects with respect to the molecular structure of gonadotropins is far less uniform ...
Geert Baggerman, Claeys, I., Anja Cerstiaens, Jozef Vanden Broeck, Janssen, T., Clynen, E., Vanden Broeck, Jozef, Breuer, M., Arnold De Loof, Ilse Claeys, Tom Janssen, Cerstiaens, A., Elke Clynen, Baggerman, G., De Loof, A., Michael Breuer, Schoofs, L., Liliane Schoofs   +17 more
core   +1 more source

Lipolytic activity of gonadotropins and their subunits

, 1972
The lipolytic activity of highly purified gonadotropins (LH, FSH, PMSG and hCG) and the related glycoprotein, TSH, was evaluated in rat adipose cells. It was found that LH, FSH and TSH were able to stimulate glycerol release.
Farmer, Susan W., Ramachandran, J., Papkoff, Harold   +2 more
core   +1 more source

Modulation of gonadotropins activity by antibodies

, 2019
International audienceGonadotropins are essential for reproduction control in humans as well as in animals. They are widely used all over the world for ovarian stimulation in women, spermatogenesis stimulation in men, and ovulation induction and ...
Maurel, Marie-Christine, Kara, Elodie, Dupuy, Laurence, Bouillon, Céline, Casteret, Sophie   +4 more
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source