Results 111 to 120 of about 295,380 (280)
British Journal of Haematology, EarlyView.Summary While marginal zone lymphoma (MZL) is generally indolent, outcomes following relapse remain poorly defined. This study utilized the indolent Non Follicular 10 (NF10) prospective database to characterize survival and identify prognostic drivers in patients failing initial systemic therapy. The study analysed 122 patients with relapsed MZL.
Stefano Luminari +28 more
wiley +1 more source
A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial
British Journal of Haematology, EarlyView.The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne +28 more
wiley +1 more source
, 2016 Follicular Lymphoma (FL) is a subtype of non-Hodgkin’s lymphoma. FL is a proliferation of the germinal center B cells mixed with nonmalignant cells. The genetic hallmark of FL is the translocation of T(14:18).
Miller-Schaar, Audra
core
Idiotype vaccine strategies for treatment of follicular lymphoma
, 2011 Follicular lymphoma is an indolent lymphoma associated with a relapsing course. Immunization with tumor B cell idiotype (Id; a unique variable region of surface B cell immunoglobulin) may induce humoral and cellular immune response against the tumor ...
Hemchandra Mahaseth +4 more
core +1 more source
British Journal of Haematology, EarlyView.High versus low baseline CAR‐HEMATOTOX scores were associated with poorer safety and efficacy outcomes in patients with R/R B‐NHL who received odronextamab in the ELM‐1 and ELM‐2 studies. The CAR‐HEMATOTOX score may provide a readily available measure for identifying patients at risk of inferior clinical outcomes with odronextamab treatment.
Matthew Matasar +9 more
wiley +1 more source
Transformation of follicular lymphoma [PDF]
American Journal of Hematology, 2018 Wenchee, Siow +4 more
openaire +2 more sources
British Journal of Haematology, EarlyView.Summary Younger patients with high‐risk diffuse large B‐cell lymphoma (DLBCL) frequently have unfavourable outcomes. We conducted a prospective phase II study evaluating ibrutinib plus rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone (R‐CHOEP+I) in patients aged 18–60 years with DLBCL and age‐adjusted international prognostic index ≥2.
Evgenii Shumilov +19 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Comprehensive genome and transcriptome profiling can inform the diagnosis, prognosis and management of relapsed/refractory (R/R) solid malignancies, yet its integration into clinical care has lagged despite strong biological rationale. We evaluated the clinical utility of whole genome and transcriptome analysis (WGTA) in 65 patients (37 ...
Kathleen Wee +24 more
wiley +1 more source
Case Reports in Gastrointestinal MedicineDuodenal-type follicular lymphoma (DTFL) is an uncommon and often indolent extranodal lymphoma that may be difficult to recognize when characteristic endoscopic or imaging findings are absent. We report a 60-year-old man evaluated for progressive fatigue,
Zachary Vinton +4 more
doaj +1 more source
British Journal of Haematology, EarlyView.Baseline maximum standardised uptake value does not predict survival in high‐tumour‐burden follicular lymphoma treated with first‐line immunochemotherapy, but identifies patients at risk of histological transformation: no transformation occurred below the cohort median. Its role is to guide biopsy and surveillance rather than therapeutic stratification.
Ikram Bouguern +10 more
wiley +1 more source