Results 231 to 240 of about 268,333 (327)

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Basal androgen status as a modifiable predictor of poor ovarian response in controlled ovarian hyperstimulation. [PDF]

Front Reprod Health
Münch ML, Bender U, Marshall A, Guezel T, Spaich K, Germeyer A, Krivega M, Strowitzki T, Capp E, Rehnitz J.   +9 more
europepmc   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Comparing the Effects of Glyphosate and Mycotoxins in the Human Follicular Microenvironment: An Exploratory Exposome Study. [PDF]

Biomedicines
Szentirmay A, Unicsovics M, Ruff E, Csókay B, Sára-Popovics K, Holéci D, Buzder T, Sipos M, Martonos A, Sajgó A, Szeőcs N, Nagyéri G, Sára L, Szőke Z.   +13 more
europepmc   +1 more source

Living Together, Loving Apart: Health, Sexuality and Relationships in Middle‐Aged and Older Men in Europe

Andrology, EarlyView.
ABSTRACT Background Over time, family structures have grown more complex, diversifying adult relationships. While research has compared marital, cohabiting and living apart together relationships based on quality and health, less is known about their sexual dynamics.
Clotilde Sparano, Giammarco Alderotti, Giulia Rastrelli, Giovanni Corona, Leen Antonio, Felipe F. Casanueva, Aleksander Giwercman, Thang S. Han, Ilpo T. Huhtaniemi, Chiara Lucchi, Terence O'Neill, Jolanta Słowikowska‐Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick Wu, Daniele Vignoli, Mario Maggi   +16 more
wiley   +1 more source

Pituitary-derived Follicle stimulating hormone has greater follicle-stimulating bioactivity than recombinant Follicle stimulating hormone possibly due to glycoform variants†. [PDF]

Biol Reprod
Wu Z, Sun N, Tang J, Xu L, Zhou X, Jiang M, Cheng J, Zhu X, Liu M, Yang L, Davis JS, Hua G.   +11 more
europepmc   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

Expression pattern of <i>SMAD8</i> in geese at different reproductive stages and its effect on reproductive physiology and egg production performance. [PDF]

J Adv Vet Anim Res
Yu D, Zhang R, He Y, Ge K.
europepmc   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source