Results 41 to 50 of about 821,539 (207)

EVALUATION OF THYROID NODULES USING THYROID PEROXIDASE AND GALECTIN-3:AN IMMUNOHISTOCHEMICAL STUDY [PDF]

Zagazig University Medical Journal, 2013
Background and aim: Thyroid gland carcinoma is a very prevalent neoplasia worldwide. The majority of malignant and benign lesions of the thyroid can be cytologically established.
El-kateb I., Magdy Ahmed, Samah Mohammed, Mona Mostafa   +3 more
doaj   +1 more source

Thyroid Papillary Carcinoma Follicular Variant: Which Surgical Approach?

, 2014
In general, fine needle aspiration biopsy (FNAB) is insufficient and inadequate in the diagnosis of follicular variant of thyroid papillary carcinoma. Especially in capsulated forms of the carcinoma, diagnostic difficulties are pronounced because of the ...
M. Gazi Yıldız, Aydın, Sedat, Mustafa Paksoy, Gül, Aylin Ege, Aylin Ege Gül, Şanlı, Arif, Sedat Aydın, Paksoy, Mustafa, Arif Şanlı, Gazi Yıldız, M.   +9 more
core   +1 more source

Evaluation of the first automated thyroglobulin assay [PDF]

, 1999
The aim of this study was to investigate technical and analytical performance of the first automated thyroglobulin (Tg) assay (DPC-Immulite(R); Diagnostic Products Corporation, Los Angeles, USA).
Jacob, Karl, Seidel, Dietrich, Vogeser, Michael, Knesewitsch, Peter   +3 more
core   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Role of Twist1 transcription factor in thyroid tumor progression [PDF]

, 2011
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Interobserver agreement of Thyroid Imaging Reporting and Data System (TIRADS) and strain elastography for the assessment of thyroid nodules [PDF]

, 2013
Background: Thyroid Imaging Reporting and Data System (TIRADS) was developed to improve patient management and cost-effectiveness by avoiding unnecessary fine needle aspiration biopsy (FNAB) in patients with thyroid nodules.
Stefan Zeuzem, Herrmann, Eva, Friedrich-Rust, Mireen, Dauth, Nina, Bogdanou, Dimitra, Christian Berner, Nina Dauth, Mireen Friedrich-Rust, Bojunga, Jörg, Dimitra Bogdanou, Joerg Bojunga, Gesine Meyer, Eva Herrmann, Berner, Christian, Meyer, Gesine, Zeuzem, Stefan   +15 more
core   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Functional role of the CXCR4 chemokine receptor in thyroid cancer [PDF]

, 2009
Thyroid cancer is the most common endocrine malignancy and its incidence is increasing worldwide. We previously found that normal rat thyroid cells, transduced with papillary thyroid cancer (PTC)-related oncogenes, display an inflammatory signature, that
Avilla, Elvira
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source