Results 71 to 80 of about 14,717 (224)

ERβ Regulation of Gonadotropin Responses during Folliculogenesis

, 2021
Gonadotropins are essential for regulating ovarian development, steroidogenesis, and gametogenesis. While follicle stimulating hormone (FSH) promotes the development of ovarian follicles, luteinizing hormone (LH) regulates preovulatory maturation of ...
Eun B. Lee, Michael W. Wolfe, V. Praveen Chakravarthi, M. A. Karim Rumi   +3 more
core   +1 more source

An oocentric view of folliculogenesis and embryogenesis

Reproductive BioMedicine Online, 2007
The mammalian oocyte undertakes a highly complex journey to maturity during which it successively acquires a series of characteristics necessary for fertilization and the development of a healthy embryo. While the contribution of granulosa cells to oocyte development has been studied for many years, it has recently become apparent that the oocyte ...
Karla J, Hutt, David F, Albertini
openaire   +2 more sources

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

Increased Formation of Follicular Antrum in Aquaporin-8-Deficient Mice Is Due to Defective Proliferation and Migration, and Not Steroidogenesis of Granulosa Cells

Frontiers in Physiology, 2018
Aquaporin-8 (AQP8) is a water channel protein expressed exclusively in granulosa cells (GCs) in mouse ovary. Our previous studies of AQP8-deficient (AQP8-/-) mice demonstrated that AQP8 participates in folliculogenesis, including in the formation of ...
Dejiang Wang, Xiangjun Di, Jie Wang, Miao Li, Di Zhang, Yaxin Hou, Jiao Hu, Ge Zhang, He Zhang, Meiyan Sun, Xiangyu Meng, Xiangyu Meng, Bo Sun, Bo Sun, Chunlai Jiang, Chunlai Jiang, Tonghui Ma, Weiheng Su, Weiheng Su   +18 more
doaj   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, Volume 41, Issue 7, Page 416-458, July 2026.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility

, 2015
The postnatal mammalian ovary contains the primary follicles, each comprising an immature oocyte surrounded by a layer of somatic granulosa cells. Oocytes reach meiotic and developmental competence via folliculogenesis. During this process, the granulosa
Moll, J., Moll, Juergen, Frappart, L., Winkler, Anne, Ploubidou, Aspasia, Moll, Jürgen, Hamann, J., Hamann, Jana, Anne Winkler, Brunet, Phane, Jana Hamann, Peter Herrlich, Heuer, Heike, Aspasia Ploubidou, Herrlich, P., Marie-Hélène Verlhac, Heike Heuer, Li, Huaibiao, Herrlich, Peter, Brunet, Stéphane, Verlhac, Marie-Hélène, Ploubidou, A., Lucien Frappart, Kroll, Torsten, Kroll, T., Frappart, Lucien, Huaibiao Li, Brunet, S., Winkler, A., Jürgen Moll, Stéphane Brunet, Torsten Kroll, Li, H., Heuer, H.   +33 more
core   +1 more source

Analysis of the effect of bisphenol a on folliculogenesis in the experiment [PDF]

, 2021
Objective. The aim of our study was to analyze literature sources on the effect of bisphenol A on folliculogenesis. Materials and methods.
Lyalina, A.Yu., Silkina, Yu.V.
core  

Unique morphological characteristics in the ovary of cotton rat (Sigmodon hispidus)

The Journal of Reproduction and Development, 2020
Cotton rats (Sigmodon hispidus, CRs) are commonly used as animal models in biomedical research. However, the reproductive characteristics and ovarian development in the CRs has not been widely investigated.
Md. Rashedul ISLAM, Osamu ICHII, Teppei NAKAMURA, Takao IRIE, Md. Abdul MASUM, Marina HOSOTANI, Yuki OTANI, Yaser Hosny Ali ELEWA, Yasuhiro KON   +8 more
doaj   +1 more source

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao, Yue Xiao, Yi Cheng, Weihai Xu, Jing Shu, Shishi Li   +5 more
wiley   +1 more source

Electroacupuncture Ameliorates Premature Ovarian Insufficiency by Inhibiting METTL3‐Mediated m6A Methylation of Beclin 1 mRNA in Granulosa Cells

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
A high‐fat, high‐sugar (HFHS) diet induces premature ovarian insufficiency (POI), characterized by reduced follicular reserve, increased atresia, fibrosis, and excessive granulosa cell autophagy. Electroacupuncture (EA) at CV4, ST36, and SP6 suppresses METTL3 expression and reduces m6A methylation of Beclin1 mRNA, thereby limiting Beclin1 translation ...
Lele Ling, Sining He, Xue Zhao, Yaran Sheng, Mengying Hong, Long Yuan, Peng Liu, Boliang Ke, Bingrong Li, Bimeng Zhang   +9 more
wiley   +1 more source