Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Cancer Drugs Reimbursed with Limited Evidence on Overall Survival and Quality of Life: Do Follow-Up Studies Confirm Patient Benefits? [PDF]
Chauca Strand G+4 more
europepmc +1 more source
A Follow-up Study of The Hiparthrodesis
31 cases of the hiparthrodesis, operated in our clinic, were examined by means of questionnaire. 18 cases of which were examined clinically and radiogically with paticular emphasis on the changes in the lumbar spine, in the other hip and in the knee of operated side.
A. Matsuzaki, N. Uesaki, H. Tono
openaire +2 more sources
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Peripheral Nerve Regeneration A Follow-up Study of 3,656 World War II Injuries Veterans Administration Medical Monograph [PDF]
openalex +1 more source
Influencing factors of stroke occurrence and recurrence in hypertensive patients: A prospective follow-up studies. [PDF]
Jin Y+11 more
europepmc +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Congenital Syphilis. A Follow-up Study with Reference to Mental Abnormalities. B. Hallgren e E. Holsström [PDF]
Homero Vallada
openalex +1 more source
Predictors of Neonatal Mortality in Ethiopia: A Comprehensive Review of Follow-Up Studies. [PDF]
Girma D, Dejene H, Adugna L.
europepmc +1 more source