Results 111 to 120 of about 4,330,886 (309)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A&T Bangladesh Follow-up Survey 2016: Community

, 2016
This dataset is the result of the follow-up community survey conducted in 2016 to collect data on the sustained impacts of A&T’s behavior change communication interventions on infant and young child feeding (IYCF) practices in Bangladesh which include: 1)
International Food Policy Research Institute (IFPRI)
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Long-term follow-up after vertebroplasty - A mean 10-years follow-up control study. [PDF]

OBJECTIVES To evaluate the clinical 10 year outcome of patients treated with percutaneous vertebroplasty for vertebral compression fractures and to determine the incidence of new fractures in this time interval, as well as the mortality of the ...
Lorin Benneker, Fabian Cedric Aregger, Paul Heini, Felix Gerber, Christian Knoll, Heini, Paul, Albers, Christoph, Aregger, Fabian, Hoppe, Sven, Sven Hoppe, Oswald, Katharina, Christoph Albers, Gerber, Felix, Ulrich Berlemann, Katharina Oswald, Benneker, Lorin, Berlemann, Ulrich, Knoll, Christian   +17 more
core   +1 more source

Changes in leisure-time physical activity after transition to retirement: a follow-up study

International Journal of Behavioral Nutrition and Physical Activity, 2011
Background Retirement is a major life change that is likely to affect lifestyles. The aim of this study was to examine changes in leisure-time physical activity of moderate and vigorous intensity among ageing employees facing transition to retirement ...
Lahelma Eero, Laaksonen Mikko, Lahti Jouni, Rahkonen Ossi   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Time-to-loss to follow up by age category after adjusting for potential confounders.

, 2019
Time-to-loss to follow up by age category after adjusting for potential confounders.
Kefyalew Taye (5728922), Andrea Ruff (612071), Inger Hallstrom (7513304), Workeabeba Abebe (837416), Degu Jerene (75554)   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Time is ticking for TikTok tics: A retrospective follow‐up study in the post‐COVID‐19 isolation era

Brain and Behavior
Introduction During the COVID‐19 pandemic, an influx of adolescents presented worldwide with acute onset of functional tic‐like behaviors (FTLBs). Our goal was to evaluate psychosocial factors around onset, to elucidate outcomes after pandemic isolation ...
Kinga K. Tomczak, Jennifer Worhach, Michael Rich, Olivia Swearingen Ludolph, Susan Eppling, Georgios Sideridis, Tamar C. Katz   +6 more
doaj   +1 more source

Recommendations and definitions for time-to-event endpoints using real-world data in oncology

ESMO Real World Data and Digital Oncology
Background: Real-world data is increasingly used to assess effectiveness of treatments in patients treated in everyday clinical practice. The aim of this study is to establish definitions for time-to-event endpoints based on real-world data, and to ...
P.A.J. Vissers, M.A.G. Elferink, M.J. Bijlsma, L.G. van der Geest, M. Koopman, H.W.M. van Laarhoven, G.A.P. Nieuwenhuijzen, P.S.N. van Rossum, F.P.C. Sijtsma, G.R. Vink, J. de Vos-Geelen, H.W. Wilmink, J.H.W. de Wilt, R.H.A. Verhoeven, F.N. van Erning   +14 more
doaj   +1 more source