Results 91 to 100 of about 245,280 (285)
miRNA signatures associated with vulnerability to food addiction in mice and humans
The Journal of Clinical Investigation, 2022 Food addiction is characterized by a loss of behavioral control over food intake and is associated with obesity and other eating disorders. The mechanisms underlying this behavioral disorder are largely unknown.
Alejandra García-Blanco +14 more
doaj +1 more source
Adolescent internet abuse. A study on the role of attachment to parents and peers in a large community sample [PDF]
, 2018 Adolescents are the main users of new technologies and theirmain purpose of use is social interaction. Although new technologies are useful to teenagers, in addressing their developmental tasks, recent studies have shown that they may be an obstacle in ...
Ballarotto, Giulia +3 more
core +3 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Current Concepts on Drug Abuse and Dependence [PDF]
, 2015 Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza +5 more
core +3 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Scientific ReportsObesity and food addiction are associated with distinct brain signatures related to reward processing, and early life adversity (ELA) also increases alterations in these same reward regions.
Soumya Ravichandran +11 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
NATIVE AMERICAN OBESITY: AN ECONOMIC MODEL OF THE THRIFTY GENE THEORY [PDF]
Native American obesity and the associated health conditions are generally thought to result in part from a genetic predisposition to overeating fats and carbohydrates, called the "thrifty gene." Although coined by nutritional scientists, this study ...
Patterson, Paul M., Richards, Timothy J.
core +1 more source
The Cowl - v.81 - n.2 - Sep 15, 2016 [PDF]
, 2016 The Cowl - student newspaper of Providence College. Vol 81 - No. 2 - September 15, 2016.
core +1 more source