Results 111 to 120 of about 1,767,334 (303)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Evolution, Cost, and Operation of the Private Food Assistance Network [PDF]

Delivery of assistance to the poor has changed drastically in the past 20 years. While the availability of cash assistance has decreased, the availability of food assistance has widened. The most substantial change in assistance available to the poor may
B. O. Daponte, S. L. Bade
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Chef Charles Says..., Instructors’ Guide, May 2012 [PDF]

, 2012
The Food Assistance Program provides nutrition assistance to people with low income. Food Assistance can help you buy nutritious foods for a better diet.

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Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Public assistance, living environments, and food insecurity

Journal of Agriculture, Food Systems, and Community Development
Food insecurity continues to affect certain seg­ments of the U.S. population at the household and individual levels even when the economy is experi­encing growth.
Mesfin Bezuneh, Zelealem Yiheyis
doaj   +1 more source

Chef Charles Says..., Instructors’ Guide, May 2010 [PDF]

, 2010
The Food Assistance Program provides nutrition assistance to people with low income. Food Assistance can help you buy nutritious foods for a better diet.

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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Optimizations of α-amylase production by response surface methodology in immobilization Bacillus amyloliquefaciens ATCC 23350

Biological Journal of Microorganism, 2016
Introduction: Production of an endogenous α-amylase from Bacillus amyloliquefaciens ATCC 23350 was studied and enhanced. Materials and methods: Protein and carbon sources were analyzed for free and immobilized bacterial cells and number of beads ...
Hamid reza Samadlouie, Maryam Karimiroozbahani, Hami kaboosi, Naser Farrokhi   +3 more
doaj  

Private versus public relief: Utilization of food pantries versus food stamps among poor households in Allegheny County, Pennsylvannia [PDF]

The research presented examines the role of private versus public food assistance programs in alleviating food shortages among poor households. First, multinomial probit models are used to examine which factors affect four alternative food assistance ...
B. O. Daponte
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