Results 61 to 70 of about 422,390 (252)
Food is Medicine (FIM) strategies are designed to alleviate diet-related chronic disease by increasing access to nutritious foods. In this cross-sectional, mixed-methods study, 13 medically tailored grocery (MTG) clients utilized a mobile app to capture ...
Michael F. Royer +7 more
doaj +1 more source
This paper assesses the impact of assistance on the wellbeing of Palestinian households. The impact evaluation analysis uses a difference-in-difference approach for the treatment of sample selection bias. The paper uses data from the 2013 and 2014 rounds
Donato Romano +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Exploring scenario guided pathways for food assistance in Tuscany
A growing number of people in high income countries, also from the segments of population once considered secure, seek food assistance. Diverse food aid initiatives and practices are developed by a range of actors to tackle food poverty; alongside ...
Francesca Galli +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Background Few data are available to guide programmatic solutions to the overlapping problems of undernutrition and HIV infection. We evaluated the impact of food assistance on patient outcomes in a comprehensive HIV program in central Haiti in a ...
Ivers Louise C +3 more
doaj +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Following the COVID-19 pandemic, there has been a significant increase in collaboration between various public, private and civil organizations. These initiatives include solidarity kitchens, which are based on the principle of the Human Right to ...
Camila Lago Braga +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

