Results 141 to 150 of about 3,889,427 (292)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Does the Food Stamp Program Affect Food Security Status and the Composition of Food Expenditures? [PDF]

This article considers interaction among participation in the Food Stamp Program (FSP), food security status, and the composition of food expenditures. A quadratic almost ideal demand system with a bootstrapping two-step method of estimation is applied ...
Pan, Suwen, Jensen, Helen H.
core  

Public assistance program and food diversity among older people: a cross-sectional study using the Japan Gerontological Evaluation Study data

International Journal for Equity in Health
Background Food diversity plays an important role in people’s healthy and affluent lives. However, poverty and eating alone can create multi-dimensional barriers to food diversity.
Kotone Tanaka, Daisuke Nishioka, Atsushi Nakagomi, Keiko Ueno, Kazushige Ide, Shiho Kino, Nobuko Murayama, Katsunori Kondo   +7 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Food Not Bombs : 2007 World Food Not Bombs Gathering - Ukraine

, 2007
One of a series of posters painted by Food Not Bombs co-founder Keith McHenry to illustrate Food Not Bombs gatherings, tours or other actions. This poster depicts farmland in the background with buildings and people holding a "Food Not Bombs" banner in ...
McHenry, Keith, 1957-
core   +1 more source

Food Not Bombs : The Food Not Bombs horizontal painting

One of a series of posters painted by Food Not Bombs co-founder Keith McHenry to illustrate Food Not Bombs gatherings, tours or other actions. This poster depicts people in a park holding a "Food not Bombs" banner and serving food, a free radio booth, a ...
McHenry, Keith, 1957-
core   +1 more source

Supplemental Nutrition Assistance Program (SNAP): does receiving assistance impact food choices?

Nutrition and Dietary Supplements, 2019
Prageet K Sachdev, Mahsa Babaei, Jeanne H Freeland-GravesDepartment of Nutritional Sciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USAAbstract: The Supplemental Nutrition Assistance Program (SNAP) is the ...
Sachdev PK, Babaei M, Freeland-Graves JH
doaj  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source