Results 41 to 50 of about 3,272,864 (255)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Adolescent emotions toward sweet food cues as a function of obesity and risky dieting practices [PDF]
, 2018 This study examined whether poor health habits – those associated with a higher risk of developing eating disorders or obesity – modified adolescents’ emotions toward sweet food cues.
Sonia Rodríguez-Ruiz +11 more
core +1 more source
Maladaptive self-reported eating behaviours and attentional bias for food cues
, 2013 Worldwide rates of obesity have dramatically increased in the last few decades. The impact on those involved and on health care systems continues to be huge.
Dobinson, Stuart
core +1 more source
Frontiers in Nutrition, 2014 Emerging evidence from recent neuroimaging studies suggests specific food related behaviours contribute to the development of obesity. The aim of this review was to report the neural responses to visual food cues, as assessed by functional magnetic ...
Kirrilly ePursey +5 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
It must be my metabolism: Metabolic control of mind
Frontiers in Integrative Neuroscience, 2014 For millennia it was advantageous to overeat whenever food was available in order to create reserves of energy for likely future episodes of famine.
Dana M Small
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Sight or scent: lemur sensory reliance in detecting food quality varies with feeding ecology. [PDF]
PLoS ONE, 2012 Visual and olfactory cues provide important information to foragers, yet we know little about species differences in sensory reliance during food selection.
Julie Rushmore +2 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source