Results 31 to 40 of about 3,272,864 (255)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IntroductionThe transition from normal weight to obesity, defined as being “overweight,” represents a critical window for preventive intervention; however, it remains debated whether cognitive vulnerabilities at this stage manifest as a domain-general ...
Ningqi Yang, Hang Zheng, Bo Sun
doaj +1 more source
Coping with brief periods of food restriction: mindfulness matters
The obesity epidemic had spawned considerable interest in understanding peoples’ responses to palatable food cues that are plentiful in obesogenic environments.
Brielle ePaolini +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Food Security Simulator – Nigeria
The Food Security Simulator is an innovative and easy-to-use, MS-Excel-based tool for assessing the potential short-term impacts of food price or household income shocks on food security and people’s diets.
International Food Policy Research Institute (IFPRI)
core +1 more source
The mechanism of food detection in tadpoles of Polypedates maculatus was experimentally tested. We used a rectangular glass test tank with stimulus zones in opposite ends to provide visual and/or chemical food.
Santosh M. Mogali +2 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Hunger pain and its reduction; qualitative insight from people with schizophrenia on semaglutide
Purpose It is often reported that people with schizophrenia experience weight gain and disordered eating, partly due to antipsychotics. As part of the RCT “Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes, HISTORI ...
Belinda Sewohl Rasmussen +8 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sensorial Hierarchy in Octopus vulgaris’s Food Choice: Chemical vs. Visual
Octopus vulgaris possesses highly sophisticated sense organs, processed by the nervous system to generate appropriate behaviours such as finding food, avoiding predators, identifying conspecifics, and locating suitable habitat.
Valeria Maselli +5 more
doaj +1 more source

