Results 121 to 130 of about 354,146 (300)
Advanced Science, EarlyView.This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li +7 more
wiley +1 more source
Poverty and Inequality in the UK: 2008 [PDF]
, 2007 In this Commentary, we assess the changes to average incomes, inequality and poverty that have occurred under the first 10 years of the Labour government, with a particular focus on the changes that have occurred in the latest year of data. This analysis
Brewer, M. +3 more
core
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, EarlyView.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
Determinants of Deprivation among Part–time Cassava Farming Households in the Humid Tropi [PDF]
International Journal of Agricultural Management and Development, 2011 As cost of living rises and people’s wages / salaries do not cover their basic food and dietary needs, interest in parttime farming has risen. Part-time farming activities are being practiced by different people as a food security strategy from ...
Nsikak-Abasi A Etim +2 more
doaj
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Food deprivation alters reproductive performance of biocontrol agent Hadronotus pennsylvanicus. [PDF]
Sci Rep, 2022 Straser RK, Wilson H.
europepmc +1 more source
In Situ Characterisation of Hydrogels via Dynamic Interface Printing
Advanced Science, EarlyView.ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler +2 more
wiley +1 more source
Metabolic Profiling of the Hypothalamus of Mice during Short-Term Food Deprivation. [PDF]
Metabolites, 2022 Kim YJ +8 more
europepmc +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source