Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl+14 more
wiley +1 more source
Correction: Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns. [PDF]
Ambroz A+16 more
europepmc +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li+7 more
wiley +1 more source
Virulence-Encoding Genes Conserved in <i>Salmonella</i> Isolated From Humans, Poultry, and Seafood. [PDF]
Adesiji YO+5 more
europepmc +1 more source
Production, Acceptability and Microbiological Evaluation of Weaning Food Formulations
Mamudu Halidu Badau+2 more
openalex +1 more source
Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing
ABSTRACT Duplex Sequencing (DS) is an ultra‐accurate, error‐corrected next generation sequencing (ecNGS) technology for mutation analysis. A working group (WG) within Health and Environmental Sciences Institute's Genetic Toxicology Technical Committee is investigating the suitability of ecNGS for regulatory mutagenicity testing, using DS as a model ...
Shaofei Zhang+23 more
wiley +1 more source
Draft genome sequence of a multidrug-resistant <i>Escherichia coli</i> O13/O129:H11 isolate from imported beef in Saudi Arabia. [PDF]
Aljurayyad OI+12 more
europepmc +1 more source
A Microbiological Assessment of On-Farm Food Safety Cleaning Methods in Broiler Barns
Patrick J. Ward+3 more
openalex +1 more source
Critical Evaluation of Methods for the Identification of Aneugens
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun+8 more
wiley +1 more source