Results 281 to 290 of about 3,135,952 (358)

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Correction: Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns. [PDF]

open access: yesFront Toxicol
Ambroz A   +16 more
europepmc   +1 more source

Food Safety Knowledge of Consumers and the Microbiological and Temperature Status of Their Refrigerators

open access: bronze, 2005
Jean Kennedy   +5 more
openalex   +1 more source

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li   +7 more
wiley   +1 more source

Virulence-Encoding Genes Conserved in <i>Salmonella</i> Isolated From Humans, Poultry, and Seafood. [PDF]

open access: yesJ Trop Med
Adesiji YO   +5 more
europepmc   +1 more source

Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Duplex Sequencing (DS) is an ultra‐accurate, error‐corrected next generation sequencing (ecNGS) technology for mutation analysis. A working group (WG) within Health and Environmental Sciences Institute's Genetic Toxicology Technical Committee is investigating the suitability of ecNGS for regulatory mutagenicity testing, using DS as a model ...
Shaofei Zhang   +23 more
wiley   +1 more source

Draft genome sequence of a multidrug-resistant <i>Escherichia coli</i> O13/O129:H11 isolate from imported beef in Saudi Arabia. [PDF]

open access: yesMicrobiol Resour Announc
Aljurayyad OI   +12 more
europepmc   +1 more source

A Microbiological Assessment of On-Farm Food Safety Cleaning Methods in Broiler Barns

open access: hybrid, 2006
Patrick J. Ward   +3 more
openalex   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun   +8 more
wiley   +1 more source

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