A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee +6 more
wiley +1 more source
Gap between national food production and food-based dietary guidance highlights lack of national self-sufficiency. [PDF]
Stehl J +4 more
europepmc +1 more source
Cereals, the world food problem and UK self-sufficiency [PDF]
openaire +2 more sources
FOOD SELF-SUFFICIENCY IN LATVIA: LOCAL FOOD VERSUS IMPORTED FOOD
openaire +2 more sources
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Associations Between Micronutrient Sufficiency, Subjective Well-Being, and Mortality Among Community-Dwelling Chinese Adults. [PDF]
Fan L, Liu M, Tian X, Chen A, Dang Y.
europepmc +1 more source
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source
Usability, acceptability, and perceived relevance of the observatory of chronic health conditions of Santa Catarina: a formative evaluation. [PDF]
Will Castro LSEP +6 more
europepmc +1 more source
SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen +20 more
wiley +1 more source
Economic shocks, food insufficiency and mental health: Evidence from the COVID-19 pandemic. [PDF]
Pan Y, Fan L, Goetz S.
europepmc +1 more source

