Results 141 to 150 of about 5,347,238 (307)

The architecture of predator-prey and the relationship between complexity and stability [PDF]

, 2010
Theoretical studies predict that the stability of an ecosystem is negatively correlated with its complexity, measured by the number of interacting species. On the other hand, empirical evidence indicates that food webs are highly interconnected.
Chrystian Paixao, Iraziet Charret, Jose Alberto Nogales Vera, Karen Luz Burgoa Rosso, Lucas Faria   +4 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Measuring food quality: concepts, methods and challenges - Proceedings seminar February 2007 [PDF]

, 2007
From 12 to 14 February, the Louis Bolk Instituut organised the 3rd annual QLIF workshop, titled “Measuring food quality, concepts, methods and challenges”. During these days a diverse and intensive program was presented.

core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Synthesizing the impact of armed conflicts on food security, livelihoods and social dynamics in Amhara region, Ethiopia

BMC Nutrition
Background Armed conflicts cause food insecurity and famine by triggering the disruption and destruction of food systems. The conflict that erupted in northern Ethiopia lasted from 2020 to 2022 and affected millions of people.
Jemal Hassen Muhyie, Desalegn Yayeh, Seblewongiel Ayenalem Kidanie, Wubshet Asnake Metekia, Temesgen Tilahun   +4 more
doaj   +1 more source

A Meta-Analysis of Genetically Modified Food Valuation Studies [PDF]

A plethora of research in recent years has been devoted to estimating consumer demand for genetically modified food, an important piece of information needed to create appropriate public policy. To examine this body of work, a meta-analysis was conducted
Jamal, Mustafa, Kurlander, Lauren, Lusk, Jayson L., Roucan, Maud, Taulman, Lesley   +4 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source