Results 81 to 90 of about 25,598,393 (357)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Chemometrics in Laboratory Data Analysis

open access: yesТехника и технология пищевых производств
Food is a complex system that requires holistic quality assessment. Chemometrics uses mathematical, statistical, and computer science methods to analyze and interpret chemical data, which means good prospects for food quality evaluation.
Lisitsyn Andrey   +3 more
doaj   +1 more source

Good Questions 11: Where are governments’ plans for dealing with food system disruptions?

open access: yesWorld Nutrition, 2020
In April 2020, when most businesses in the United States were shut down because of Covid-19, many people became unemployed and their incomes vanished.
George Kent
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Food systems transformation commitments in Eastern Africa and their alignment with the UNFSS action areas and the Kampala CAADP Declaration

open access: yesFrontiers in Sustainable Food Systems
As we approach 2030, Africa remains distant from achieving the second sustainable development goal of zero hunger. Approximately 307 million people in Africa experience hunger, a number that may continue to rise.
Sofia Jomo   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Formation of MeIQx and PhIP in model matrices from amino acids, carbohydrates, and creatine

open access: yesПищевые системы
The understanding of the reaction of HAA formation in foods is a key for finding methods for reduction of their quantity. Currently, more and more experimental works are dedicated to the question of HAA formation in model matrices to establish the main ...
D. A. Utyanov   +3 more
doaj   +1 more source

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