Results 101 to 110 of about 3,511,428 (312)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Economic Evaluation of Food Traceability Systems through Reference Models [PDF]
Food supply chains complexity present a real challenge to perform economic evaluation of food traceability systems and their innovation/upgrades. In order to perform a supply chain wide economic evaluation a conceptual framework is developed using food ...
Brofman, Freddy +2 more
core +1 more source
The four food systems in developing countries and the challenges of modern supply chain inclusion for organic small-holders [PDF]
, 2009 To promote developmental objectives, such as growth, food security and improvement of the livelihoods of the rural poor, a greater understanding of the four food systems prevalent in the South is of great importance.
Kledal, P.R.
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
No. 12: Compounding Vulnerability: A Model of Urban Household Food Security [PDF]
, 2017 The efficiency of the infrastructure systems in cities will define the extent to which dystopic visions of urban futures become a reality. At the level of the individual household, vulnerability to hazards in cities is defined, in part, by the ability to
McCordic, Cameron
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
CONSUMER DEMAND FOR TRACEABILITY [PDF]
Consumers have become more discerning in their food consumption choices. Food safety and food quality issues have moved to the forefront of consumer concerns, industry strategies, and in some cases, government policy.
Hobbs, Jill E.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2006 The introductory chapter describes the challenge and notes the complex of rural problem, associated with food systems, with focus on those in countries bordering the Baltic Sea.
Kahiluoto, Helena
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source