Results 91 to 100 of about 2,840,144 (244)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Primary consumers as bioindicator of nitrogen pollution in lake planktonic and benthic food webs

, 2012
The increased nitrogen loading from anthropogenic sources has affected aquatic ecosystems and has cascaded through food webs worldwide. Therefore, the evaluation of ecological impacts of anthropogenic nitrogen has become increasingly important.
Xu, Jun, Zhang, M (reprint author), Huazhong Agr Univ, Coll Fisheries, Wuhan 430070, Peoples R China, Zhang, Min   +2 more
core   +1 more source

Eco-Evolutionary Origins of Diverse Abundance, Biomass, and Trophic Structures in Food Webs

Frontiers in Ecology and Evolution, 2019
Organismal traits and their evolution can strongly influence food web structure and dynamics. To what extent the evolution of such traits impacts food web structure, however, is poorly understood. Here, we investigate a simple three-species omnivory food
Jean P. Gibert, Jean P. Gibert, Justin D. Yeakel   +2 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Species' traits and food‐web complexity interactively affect a food web's response to press disturbance

Ecosphere, 2016
Given current levels of biodiversity loss and environmental change, studies of how food webs respond to disturbance should broaden their focus beyond short‐term disturbances to explore the effects of long‐term, “press” disturbances.
K. L. Wootton, D. B. Stouffer
doaj   +1 more source

Essential Biomolecules in Food Webs

Frontiers in Ecology and Evolution, 2019
We here review the ecological role of essential nutritional biomolecules [fatty acids (FA), amino acids (AA), sterols, vitamins] in aquatic and terrestrial food webs, encompassing the forces behind their environmental distribution.
Liliane Ruess, Dörthe C. Müller-Navarra   +1 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

Stochastic webs and quantum transport in superlattices : an introductory review. [PDF]

, 2009
Stochastic webs were discovered, first by Arnold for multi-dimensional Hamiltonian systems, and later byChernikov et al. for the low-dimensional case. Generated by weak perturbations, they consist of thread-like regions of chaotic dynamics in phase space.
Khovanov, I. A., Fromhold T. M., MANNELLA, RICCARDO, Soskin, Stanislav M., Fromhold, T. M., Khovanov I. A., McClintock, P. V. E., Soskin S. M., Mannella, R., McClintock P. V. E., Soskin, S. M.   +10 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Mitigating impacts of climate change in stream food webs [PDF]

, 2013
Understanding the effects of changing climates on the processes which support aquatic biodiversity is of critical importance for managing aquatic ecosystems.
Ross Thompson, John Beardall, Jason Beringer   +2 more
core