Results 111 to 120 of about 282,050 (325)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Calcium Chloride Treatment Enhances Antigen Production in Foot-and-Mouth Disease Vaccines for Serotypes SAT1 and SAT3

Vaccines
Foot-and-mouth disease (FMD) is a highly contagious viral infection causing acute and severe vesicular lesions in cattle and pigs, which has prompted global vaccination policies. This study presents a technique for enhancing antigen yield in SAT1 BOT and
Dohyun Kim, Sun Young Park, Gyeongmin Lee, Eun-Sol Kim, Jong-Sook Jin, Jae Young Kim, SooAh Lee, Jong-Hyeon Park, Young-Joon Ko   +8 more
doaj   +1 more source

Epidemiology of hand, foot and mouth disease in China, 2008 to 2015 prior to the introduction of EV-A71 vaccine

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017
Introduction Hand, foot and mouth disease (HFMD) is usually caused by several serotypes from human enterovirus A species, including enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16).
Bingyi Yang, Fengfeng Liu, Q. Liao, Peng Wu, Z. Chang, Jiao Huang, L. Long, L. Luo, Yu Li, G. Leung, B. Cowling, Hongjie Yu   +11 more
semanticscholar   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010–2016

Emerging Infectious Diseases, 2018
Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015.
Yu Li, Z. Chang, Peng Wu, Q. Liao, Fengfeng Liu, Yaming Zheng, L. Luo, Yonghong Zhou, Qi Chen, Shuan-bao Yu, Chun Guo, Zhenhua Chen, L. Long, Shanlu Zhao, Bingyi Yang, Hongjie Yu, B. Cowling   +16 more
semanticscholar   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Foot-and-mouth disease attributed to serotype A in sheep flocksof Jammu and Kashmir, India

Indian Journal of Animal Sciences
The present study investigates the suspected FMD outbreak in sheep flock in Jammu and Kashmir Union Territory of India during May 2021. Swab materials, saliva and serum samples from symptomatic and in-contact apparently healthy animals were collected. A
MANORANJAN ROUT, SHABIR AHMAD KHAN, SUHAIL NABI MAGRAY, PRIYABRATA GIRI, PRIYANKA BHASKARRAO PHARANDE, JAJATI KESHARI MOHAPATRA, MOHAMMAD MAROOF SHAH, RABINDRA PRASAD SINGH   +7 more
doaj   +1 more source

An Optimal Surveillance Measure Against Foot-and-Mouth Disease in the United States [PDF]

Surveillance programs on farms and in the local environment provide an essential protection against the importation and spread of exotic diseases. Combined with border quarantine measures, these programs protect both consumers and producers from major ...
Che, Tuong Nhu, Kompas, Tom, van Ha, Pham   +2 more
core   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Transmission of Foot-and-Mouth Disease from Persistently Infected Carrier Cattle to Naive Cattle via Transfer of Oropharyngeal Fluid

Msphere, 2018
Foot-and-mouth disease (FMD) is a viral disease of livestock with substantial impact on agricultural production and subsistence farming on a global scale.
J. Arzt, G. Belsham, L. Lohse, A. Bøtner, C. Stenfeldt   +4 more
semanticscholar   +1 more source