Results 111 to 120 of about 82,160 (323)

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Evaluation of applied foot and mouth disease-providing measures in the Republic of Armenia: A retrospective study

Open Veterinary Journal
Background: Foot-and-mouth disease (FMD) is a highly contagious viral disease that affects livestock and causes significant economic losses. Control of FMD relies on culling infected animals and implementing comprehensive vaccination programs.
Henrik E. Voskanyan, Tigran H. Markosyan, Jon T. Simonyan, Mariam S. Mirzoyan, Nelli A. Shahazizyan, Levon M. Minasyan, Satenik A. Kharatyan, Liana L. Simonyan   +7 more
doaj   +1 more source

Full Genome Sequencing Reveals New Southern African Territories Genotypes Bringing Us Closer to Understanding True Variability of Foot-and-Mouth Disease Virus in Africa

Viruses, 2018
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hooved animals that poses a constant burden on farmers in endemic regions and threatens the livestock industries in disease-free countries.
Lidia Lasecka-Dykes, Caroline F. Wright, Antonello Di Nardo, Grace Logan, Valerie Mioulet, Terry Jackson, Tobias J. Tuthill, Nick J. Knowles, Donald P. King   +8 more
doaj   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies, De Vlieger, Dorien, Rossey, Iebe, Saelens, Xavier, Schepens, Bert   +4 more
core   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

Multiple human herpesvirus-8 infection [PDF]

, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM, Cook, RD, Hodgson, TA, Kondowe, W, Molyneux, EM, Porter, SR, Scully, CM, Teo, CG   +7 more
core   +1 more source

Relational Wellbeing Amongst Care‐Experienced Young People in Transition in the Context of Covid 19

Child &Family Social Work, EarlyView.
ABSTRACT Care‐experienced young people typically negotiate the transition to adulthood at a younger age than their peers in the general population and with less reliable access to support. Concerns have been raised that Covid 19 exacerbated the challenges they faced and widened the ‘care‐gap’.
Emily R. Munro, Seana Friel, Amy Lynch
wiley   +1 more source

The economic effect of discrimination: Evidence from the restaurant sector

Contemporary Economic Policy, Volume 43, Issue 2, Page 226-259, April 2025.
Abstract Discrimination often leads to economic consequences for affected groups. This study examines the economic impact of consumer discrimination on Chinese restaurants in the U.S. during the COVID‐19 pandemic's onset. Using cell phone data and revenue records, it identifies a significant −10% relative decline in visits to Chinese restaurants by ...
Guanting Yi
wiley   +1 more source

Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman, Pelin Sagut, Kathryn Lynam, Amanda Ederle, Laura Winterfield   +4 more
wiley   +1 more source