Results 1 to 10 of about 4,158 (194)

Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus [PDF]

Veterinary Medicine and Science
Bovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi, Tatsuya Nishi, Kazuki Morioka, Katsuhiko Fukai   +3 more
doaj   +3 more sources

Equine Rhinitis A Virus and Its Low pH Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?

PLoS Pathogens, 2009
Equine rhinitis A virus (ERAV) is closely related to foot-and-mouth disease virus (FMDV), belonging to the genus Aphthovirus of the Picornaviridae. How picornaviruses introduce their RNA genome into the cytoplasm of the host cell to initiate replication ...
Tobias J Tuthill, Karl Harlos, Thomas S Walter   +2 more
exaly   +6 more sources

Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. [PDF]

PLoS Pathogens, 2017
Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the ...
Elisabetta Groppelli, Hazel C Levy, Eileen Sun, Mike Strauss, Clare Nicol, Sarah Gold, Xiaowei Zhuang, Tobias J Tuthill, James M Hogle, David J Rowlands   +9 more
doaj   +4 more sources

Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids [PDF]

Viruses
A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel, Jianqiang Zhang, Huigang Shen, Anugrah Saxena, Jennifer Groeltz-Thrush, Ganwu Li, Michael C. Rahe   +6 more
doaj   +2 more sources

The structural polypeptides of aphthovirus are phosphoproteins. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1980
Analysis of aphthovirus A12, strain 119ab, grown in the presence of inorganic 32P revealed that two of the major viral polypeptides, VP4 and trypsin-sensitive protein VP3, were highly phosphorylated. The other major polypeptides, VP1 and VP2, were also phosphorylated but to a much lesser extent.
J L, La Torre, M J, Grubman, B, Baxt, H L, Bachrach   +3 more
exaly   +3 more sources

Isolation and characterization of recombinants between attenuated and virulent aphthovirus strains [PDF]

Journal of Virology, 1987
A guanidine-resistant mutant of the attenuated strain of aphthovirus type 01 strain Campos and the original wild-type strain were crossed to generate recombinant viruses. Two independently derived recombinant viruses were isolated. One isolate (RI) contained the P1 (structural proteins) gene region of attenuated strain and P3 (polymerase precursor ...
A T, Giraudo, A, Sagedahl, I E, Bergmann, J L, La Torre, E A, Scodeller   +4 more
exaly   +3 more sources

Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors [PDF]

Virulence
Foot-and-mouth disease virus (FMDV) can cause a severe infectious disease that primarily affects even-toed ungulates. FMDV is classified into the genus of Aphthovirus in the family Picornaviridae.
Houcheng Zhou, Mengyao Wang, Zuo Xin, Zhijuan Li, Qianqian Wang, Yan Li, Fuxiao Liu   +6 more
doaj   +2 more sources

Cell Entry of the Aphthovirus Equine Rhinitis A Virus Is Dependent on Endosome Acidification [PDF]

Journal of Virology, 2010
ABSTRACT Equine rhinitis A virus (ERAV) is genetically closely related to foot-and-mouth disease virus (FMDV), and both are now classified within the genus Aphthovirus of the family Picornaviridae .
Elisabetta Groppelli, Tobias J Tuthill, David J Rowlands   +2 more
exaly   +3 more sources

Behavior of intertypic recombinants between virulent and attenuated aphthovirus strains in tissue culture and cattle [PDF]

Journal of Virology, 1988
Two aphthovirus intertypic recombinants between the virulent strain A Venceslau and guanidine-resistant attenuated mutants of either strain C3 Resende or O1 Campos were obtained in an attempt to establish the region(s) of the viral genome responsible for attenuation in cattle. Recombinants that inherited the 3' half of the genome from either attenuated
A T, Giraudo, I, Gomes, P A, de Mello, E, Beck, J L, La Torre, E A, Scodeller, I E, Bergmann   +6 more
exaly   +3 more sources

Involvement of the Aphthovirus RNA Region Located between the Two Functional AUGs in Start Codon Selection

Virology, 1999
Initiation of translation in picornavirus RNAs occurs internally, mediated by an element termed internal ribosome entry site (IRES). In the aphthovirus RNA, the IRES element directs translation initiation at two in-frame AUGs separated by 84 nucleotides.
Sonia Lopez de Quinto, Encarnación Martínez-Salas   +1 more
exaly   +3 more sources