Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids [PDF]
VirusesA diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel +6 more
doaj +3 more sources
Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism?
PLoS Pathogens, 2009 Equine rhinitis A virus (ERAV) is closely related to foot-and-mouth disease virus (FMDV), belonging to the genus Aphthovirus of the Picornaviridae. How picornaviruses introduce their RNA genome into the cytoplasm of the host cell to initiate replication ...
Tobias J Tuthill +7 more
doaj +6 more sources
Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus [PDF]
Veterinary Medicine and ScienceBovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi +3 more
doaj +3 more sources
The cleavage activities of aphthovirus and cardiovirus 2A proteins.
Journal of General Virology, 1997 The primary 2A/2B polyprotein cleavage of aphtho-and cardioviruses is mediated by their 2A proteins cleaving C-terminally. Whilst the aphthovirus 2A region is only 16 aa (possibly 18 aa) long, the cardiovirus 2A protein is some 150 aa. We have previously shown that foot-and-mouth disease virus (FMDV) 2A is able to mediate cleavage in an artificial ...
M L, Donnelly +4 more
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Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. [PDF]
PLoS Pathogens, 2017 Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the ...
Elisabetta Groppelli +9 more
doaj +2 more sources
Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors [PDF]
VirulenceFoot-and-mouth disease virus (FMDV) can cause a severe infectious disease that primarily affects even-toed ungulates. FMDV is classified into the genus of Aphthovirus in the family Picornaviridae.
Houcheng Zhou +6 more
doaj +2 more sources
Electrofocusing Structural and Induced Proteins of Aphthovirus
, 1983 Electrofocusing separates ampholytes such as proteins according to their isoelectric point. Different versions of the technique have been described under various unwieldy names such as isoelectric focusing or non-equilibrium pH-gradient electrophoresis, but we prefer to apply the term electrofocusing to any type of pH-gradient electrophoresis.
A M, King +4 more
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Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation. [PDF]
PLoS Pathogens, 2017 Foot-and-mouth disease virus (FMDV) belongs to the Aphthovirus genus of the Picornaviridae, a family of small, icosahedral, non-enveloped, single-stranded RNA viruses.
Nayab Malik +8 more
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Effect of Expression of the Aphthovirus Protease 3C on Viral Infection and Gene Expression
Virology, 1995 Cells transformed with specific regions of the foot-and-mouth disease virus (FMDV) genome have been constructed and analyzed with respect to viability and susceptibility to FMDV infection. Constitutive expression of an active protease 3C under the control of the tk promoter has been documented by the ability of transformed cells to catalyze the ...
Martı́nez-Salas, Encarnación +1 more
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Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe
Infection, Genetics and Evolution, 2005 RNA viruses replicate as complex distributions of non-identical but closely related variant genomes termed viral quasispecies. When the error rate during genome replication exceeds a threshold value, the genetic information cannot be maintained and the system enters error catastrophe.
Gonzalez-Lopez, Claudia +3 more
openaire +5 more sources