Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus [PDF]
Bovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi +3 more
doaj +3 more sources
Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids [PDF]
A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel +6 more
doaj +2 more sources
The structural polypeptides of aphthovirus are phosphoproteins. [PDF]
Analysis of aphthovirus A12, strain 119ab, grown in the presence of inorganic 32P revealed that two of the major viral polypeptides, VP4 and trypsin-sensitive protein VP3, were highly phosphorylated. The other major polypeptides, VP1 and VP2, were also phosphorylated but to a much lesser extent.
B Baxt, M J Grubman, J L la Torre
exaly +3 more sources
Molecular Evolution and Epidemiological Dynamics of Foot-and-Mouth Disease Virus O/ME-SA/Ind-2001e Circulating in East Java, Indonesia, in 2022-2025. [PDF]
Background Indonesia has been free from foot‐and‐mouth disease virus (FMDV) for decades, but in April 2022, the first major re‐emerging of FMDV was detected in Gresik, East Java, and later spreading nationwide. To understand how dynamic virus spread occurs in Indonesia, we performed an epidemiological study and molecular evolution analyses.
Dinana Z +12 more
europepmc +2 more sources
Immunohistochemical Detection of Foot-and-Mouth Disease Virus in Carrier African Buffalo (Syncerus caffer). [PDF]
FMD viral antigen was consistently associated with the vasculature of the coronary band and interdigital skin as well as in the lungs. The IHC results revealed a novel association of viral antigen with vascular tissue and demonstrated the potential for superior sensitivity over PCR. ABSTRACT Background African buffalo are long‐term carriers of foot‐and‐
Henning A, Quan M, Loots A, Odendaal L.
europepmc +2 more sources
Cell Entry of the Aphthovirus Equine Rhinitis A Virus Is Dependent on Endosome Acidification [PDF]
ABSTRACT Equine rhinitis A virus (ERAV) is genetically closely related to foot-and-mouth disease virus (FMDV), and both are now classified within the genus Aphthovirus of the family Picornaviridae .
David Rowlands +2 more
exaly +3 more sources
Evaluation of Direct Economic Losses Due to Foot and Mouth Disease Reported by the Epidemiological Surveillance System in Cameroon From 2009 to 2023. [PDF]
The economic impact of FMD in Cameroon from 2009 to 2023 is determined by evaluating immediate, evident production losses, such as mortality losses, drop in milk production, and veterinary cost, which are usually faced by farmers. The expected total direct economic losses were USD 898,170.
Bayang HN +5 more
europepmc +2 more sources
Location of an Immunizing Determinant within Polypeptide VP1 of Type O Aphthovirus
VP1 is the only structural polypeptide of aphthovirus able to stimulate the production of neutralizing antibody. The region of VP1 responsible for this activity was located by testing various proteolytic fragments of VP1 for their ability to compete for virus-specific antibodies in serum raised against the intact polypeptide.
D Mccahon, A M KING
exaly +3 more sources
Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors [PDF]
Foot-and-mouth disease virus (FMDV) can cause a severe infectious disease that primarily affects even-toed ungulates. FMDV is classified into the genus of Aphthovirus in the family Picornaviridae.
Houcheng Zhou +6 more
doaj +2 more sources
Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications. [PDF]
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Sun Y +19 more
europepmc +2 more sources

