Results 11 to 20 of about 4,158 (194)

Heat shock protein 90 chaperone activity is required for hepatitis A virus replication [PDF]

Journal of Virology
HSP90 heat shock chaperones are essential for maintaining cellular proteostasis, as well as the ATP-dependent folding and functional maturation of many viral proteins. As a result, inhibitors of HSP90 have broad antiviral activity, disrupting replication
You Li, Xin Zheng, Ling Xie, Maryna Kapustina, Takayoshi Shirasaki, Bryan Yonish, Xian Chen, Asuka Hirai-Yuki, Noriyo Nagata, Ryosuke Suzuki, Masanori Isogawa, Matthew R. Vogt, Masamichi Muramatsu, Stanley M. Lemon   +13 more
doaj   +2 more sources

Molecular characterization of VP1 gene during the foot and mouth disease virus outbreak in East Java, Indonesia, in 2022 [PDF]

Veterinary World
Background and Aim: Foot and mouth disease (FMD) is highly contagious in cloven-hoofed animals, and it causes outbreaks in Indonesia and several countries worldwide.
Zayyin Dinana, Suwarno Suwarno, Imam Mustofa, Jola Rahmahani, Kusnoto Kusnoto, Aussie Tahta Maharani, Anisa Lailatul Fitria, Adiana Mutamsari Witaningrum, Firdausy Kurnia Maulana, Nur Saidah Said, Deka Uli Fahrodi, Fedik Abdul Rantam   +11 more
doaj   +2 more sources

Conservation of the secondary structure elements of the 5' untranslated region of cardio- and aphthovirus RNAs

Nucleic Acids Research, 1989
An analysis of published nucleotide sequences of the 5'-untranslated region (5'-UTR) of 7 cardioviruses and 3 aphthoviruses has allowed us to derive a consensus secondary structure model that differs from that previously proposed for the 5'-UTR of entero- and rhinoviruses, though all these viruses belong to the same family, Picornaviridae.
E V, Pilipenko, V M, Blinov, B K, Chernov, T M, Dmitrieva, V I, Agol   +4 more
exaly   +4 more sources

Conserved tertiary structural elements in the 5’ nontranslated region of cardiovirus, aphthovirus and hepatitis A virus RNAs

Nucleic Acids Research, 1993
Statistical analyses of RNA folding in 5' nontranslated regions (5'NTR) of encephalomyocarditis virus, Theiler's murine encephalomyelitis virus, foot-and-mouth disease virus, and hepatitis A virus indicate that two highly significant folding regions occur in the 5' and 3' portions of the 5'NTR.
Nahum Sonenberg
exaly   +4 more sources

Cryo-EM structure of the Seneca Valley virus A-particle and related structural states [PDF]

Journal of Virology
Picornavirus cell entry requires a series of capsid protein conformational changes leading to genome uncoating. For enteroviruses, receptor binding triggers the transition from a full (F) capsid to an altered (A) particle before releasing its genome and ...
Rosheny Kumaran, Nadishka Jayawardena, Kuan-Lin Chen, Alice-Roza Eruera, James Hodgkinson-Bean, Laura N. Burga, Matthias Wolf, Mihnea Bostina   +7 more
doaj   +2 more sources

Molecular Evolution and Epidemiological Dynamics of Foot-and-Mouth Disease Virus O/ME-SA/Ind-2001e Circulating in East Java, Indonesia, in 2022-2025. [PDF]

Vet Med Int
Background Indonesia has been free from foot‐and‐mouth disease virus (FMDV) for decades, but in April 2022, the first major re‐emerging of FMDV was detected in Gresik, East Java, and later spreading nationwide. To understand how dynamic virus spread occurs in Indonesia, we performed an epidemiological study and molecular evolution analyses.
Dinana Z, Rahmahani J, Suwarno, Hamid IS, Al-Arif MA, Yunus M, Tyasningsih W, Ihsan IS, Maharani AT, Maulana FK, Said NS, Fahrodi DU, Rantam FA.   +12 more
europepmc   +2 more sources

Immunohistochemical Detection of Foot-and-Mouth Disease Virus in Carrier African Buffalo (Syncerus caffer). [PDF]

Vet Med Sci
FMD viral antigen was consistently associated with the vasculature of the coronary band and interdigital skin as well as in the lungs. The IHC results revealed a novel association of viral antigen with vascular tissue and demonstrated the potential for superior sensitivity over PCR. ABSTRACT Background African buffalo are long‐term carriers of foot‐and‐
Henning A, Quan M, Loots A, Odendaal L.
europepmc   +2 more sources

Evaluation of Direct Economic Losses Due to Foot and Mouth Disease Reported by the Epidemiological Surveillance System in Cameroon From 2009 to 2023. [PDF]

Vet Med Sci
The economic impact of FMD in Cameroon from 2009 to 2023 is determined by evaluating immediate, evident production losses, such as mortality losses, drop in milk production, and veterinary cost, which are usually faced by farmers. The expected total direct economic losses were USD 898,170.
Bayang HN, Mouiche Mouliom MM, Mpouam SE, Feussom Kameni JM, Moffo F, Kilekoung JPM.   +5 more
europepmc   +2 more sources

Foot-and-Mouth Disease Virus Interserotypic Recombination in Superinfected Carrier Cattle

Pathogens, 2022
Viral recombination contributes to the emergence of novel strains with the potential for altered host range, transmissibility, virulence, and immune evasion.
Ian Fish, Carolina Stenfeldt, Edward Spinard, Gisselle N. Medina, Paul A. Azzinaro, Miranda R. Bertram, Lauren Holinka, George R. Smoliga, Ethan J. Hartwig, Teresa de los Santos, Jonathan Arzt   +10 more
doaj   +1 more source

Full-length genomic analysis of korean porcine sapelovirus strains. [PDF]

, 2014
Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, is associated with diarrhea, pneumonia, severe neurological disorders, and reproductive failure in pigs.
Deok-Song Kim, Graham J Belsham, Jong-Soon Choi, Joseph Kwon, Kyoung-Oh Cho, Kyu-Yeol Son, Mun-Il Kang, Mun-Il Kang   +7 more
core   +10 more sources