Results 41 to 50 of about 2,793 (153)

Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe

Infection, Genetics and Evolution, 2005
RNA viruses replicate as complex distributions of non-identical but closely related variant genomes termed viral quasispecies. When the error rate during genome replication exceeds a threshold value, the genetic information cannot be maintained and the system enters error catastrophe.
Gonzalez-Lopez, Claudia, Gomez-Mariano, Gema, Escarmis, Cristina, Domingo, Esteban   +3 more
openaire   +4 more sources

Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.

PLoS Pathogens, 2017
Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the ...
Elisabetta Groppelli, Hazel C Levy, Eileen Sun, Mike Strauss, Clare Nicol, Sarah Gold, Xiaowei Zhuang, Tobias J Tuthill, James M Hogle, David J Rowlands   +9 more
doaj   +1 more source

Spatial Risk Factors Influencing on the Occurrence of Foot and Mouth Disease Outbreaks in Karnataka

International Journal of Infectious Diseases, 2022
Purpose: Foot and Mouth disease (FMD) is extremely infectious viral disease of cloven-hoofed animals including, cattle, buffalo, sheep, goat, pig and water buffalo and also wild species. The disease is caused by Foot and Mouth Virus (FMDV) belongs to the
V. R
doaj   +1 more source

FOOT AND MOUTH DISEASE (FMD) [PDF]

Assiut Veterinary Medical Journal
Foot-and-mouth disease (FMD) is a severe and extremely contagious viral disease. Cow, sheep, goats, deer, pigs, and other animals with divided hooves are among the animals infected by the FMD virus.
HANA RAOOF
doaj   +1 more source

Evolution of a persistent aphthovirus in cytolytic infections: partial reversion of phenotypic traits accompanied by genetic diversification [PDF]

Journal of Virology, 1996
Foot-and-mouth disease virus (FMDV) shows a dual potential to be cytolytic or to establish persistent infections in cell culture. FMDV R100, a virus rescued after 100 passages of carrier BHK-21 cells persistently infected with FMDV clone C-S8c1, showed multiple genetic and phenotypic alterations relative to the parental clone C-S8c1.
N, Sevilla, E, Domingo
openaire   +2 more sources

Structures and Corresponding Functions of Five Types of Picornaviral 2A Proteins

Frontiers in Microbiology, 2017
Among the few non-structural proteins encoded by the picornaviral genome, the 2A protein is particularly special, irrespective of structure or function. During the evolution of the Picornaviridae family, the 2A protein has been highly non-conserved.
Xiaoyao Yang, Xiaoyao Yang, Xiaoyao Yang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Mingshu Wang, Mingshu Wang, Mingshu Wang, Renyong Jia, Renyong Jia, Renyong Jia, Kunfeng Sun, Kunfeng Sun, Kunfeng Sun, Kangcheng Pan, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Xin-Xin Zhao, Xin-Xin Zhao, Xin-Xin Zhao, Xiaoyue Chen, Xiaoyue Chen   +34 more
doaj   +1 more source

Adverse effects of foot-and-mouth disease vaccine in dairy cattle [PDF]

Pesquisa Veterinária Brasileira, 2020
: Foot-and-mouth disease represents an important barrier to the international commerce of animal products, potentially associated with significant economic losses. The systematic vaccination of bovines and buffaloes was fundamental for the eradication of
Jasmyne A. Robattini, Rogan M. Kumer, Gabriella S. Velho, Mônica M. Buttelli, Átila C. Soares, Luis Gustavo Corbellini, André G.C. Dalto   +6 more
doaj   +1 more source

Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replication

Journal of General Virology, 2001
The 3′ noncoding region (NCR) of the genomic picornaviral RNA is believed to contain majorcis-acting signals required for negative-strand RNA synthesis. The 3′ NCR of foot-and-mouth disease virus (FMDV) was studied in the context of a full-length infectious clone in which the genetic element was deleted or exchanged for the equivalent region of a ...
Sáiz, Margarita, Gómez, Susana, Martínez-Salas, E., Sobrino Castelló, Francisco   +3 more
openaire   +3 more sources

A Comprehensive Review of the Immunological Response against Foot-and-Mouth Disease Virus Infection and Its Evasion Mechanisms

Vaccines, 2020
Foot-and-mouth disease (FMD) is a highly contagious viral disease, which has been reported for over 100 years, and against which the struggle has lasted for the same amount of time.
Ibett Rodríguez-Habibe, Carmen Celis-Giraldo, Manuel Elkin Patarroyo, Catalina Avendaño, Manuel Alfonso Patarroyo   +4 more
doaj   +1 more source

Effect of Expression of the Aphthovirus Protease 3C on Viral Infection and Gene Expression

Virology, 1995
Cells transformed with specific regions of the foot-and-mouth disease virus (FMDV) genome have been constructed and analyzed with respect to viability and susceptibility to FMDV infection. Constitutive expression of an active protease 3C under the control of the tk promoter has been documented by the ability of transformed cells to catalyze the ...
Martı́nez-Salas, Encarnación, Domingo, Esteban   +1 more
openaire   +2 more sources