Minimum energy paths for conformational changes of viral capsids [PDF]
, 2017 In this work we study how a viral capsid can change conformation using techniques of Large Deviations Theory for stochastic differential equations. The viral capsid is a model of a complex system in which many units - the proteins forming the capsomers -
Cermelli, Paolo +2 more
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Adverse effects of foot-and-mouth disease vaccine in dairy cattle [PDF]
Pesquisa Veterinária Brasileira, 2020 : Foot-and-mouth disease represents an important barrier to the international commerce of animal products, potentially associated with significant economic losses. The systematic vaccination of bovines and buffaloes was fundamental for the eradication of
Jasmyne A. Robattini +6 more
doaj +1 more source
Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication [PDF]
, 2016 The Picornaviridae is a large family of positive-sense RNA viruses that contains numerous human and animal pathogens, including foot-and-mouth disease virus (FMDV).
Ferrer-Orta, C +6 more
core +1 more source
Structures and Corresponding Functions of Five Types of Picornaviral 2A Proteins
Frontiers in Microbiology, 2017 Among the few non-structural proteins encoded by the picornaviral genome, the 2A protein is particularly special, irrespective of structure or function. During the evolution of the Picornaviridae family, the 2A protein has been highly non-conserved.
Xiaoyao Yang +34 more
doaj +1 more source
Spatial Risk Factors Influencing on the Occurrence of Foot and Mouth Disease Outbreaks in Karnataka
International Journal of Infectious Diseases, 2022 Purpose: Foot and Mouth disease (FMD) is extremely infectious viral disease of cloven-hoofed animals including, cattle, buffalo, sheep, goat, pig and water buffalo and also wild species. The disease is caused by Foot and Mouth Virus (FMDV) belongs to the
V. R
doaj +1 more source
Employing transposon mutagenesis to investigate foot-and-mouth disease virus replication [PDF]
, 2015 Probing the molecular interactions within the foot-and-mouth disease virus (FMDV) RNA replication complex has been restricted in part to the lack of suitable reagents.
Belsham +17 more
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Location of an Immunizing Determinant within Polypeptide VP1 of Type O Aphthovirus
Journal of General Virology, 1983 VP1 is the only structural polypeptide of aphthovirus able to stimulate the production of neutralizing antibody. The region of VP1 responsible for this activity was located by testing various proteolytic fragments of VP1 for their ability to compete for virus-specific antibodies in serum raised against the intact polypeptide.
J M, Haresnape, A M, King, D, McCahon
openaire +2 more sources
Detection of foot-and-mouth disease virus rna by reverse transcription loop-mediated isothermal amplification [PDF]
, 2011 A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for foot-and-mouth disease virus (FMDV) RNA. The amplification was able to finish in 45 min under isothermal condition at 64°C by employing a set of four primers
Hao-tai Chen +3 more
core +1 more source
Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replication
Journal of General Virology, 2001 The 3′ noncoding region (NCR) of the genomic picornaviral RNA is believed to contain majorcis-acting signals required for negative-strand RNA synthesis. The 3′ NCR of foot-and-mouth disease virus (FMDV) was studied in the context of a full-length infectious clone in which the genetic element was deleted or exchanged for the equivalent region of a ...
Sáiz, M. +3 more
openaire +3 more sources
Vaccines, 2020 Foot-and-mouth disease (FMD) is a highly contagious viral disease, which has been reported for over 100 years, and against which the struggle has lasted for the same amount of time.
Ibett Rodríguez-Habibe +4 more
doaj +1 more source