Results 61 to 70 of about 2,793 (153)

Identification of plasticity and interactions of a highly conserved motif within a picornavirus capsid precursor required for virus infectivity

Scientific Reports, 2019
The picornavirus family includes poliovirus (PV) (genus: enterovirus), human rhinoviruses (enterovirus) and foot-and-mouth disease virus (FMDV) (aphthovirus).
Thea Kristensen, Graham J. Belsham
doaj   +1 more source

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo

RNA, 2000
The strategies developed by internal ribosome entry site (IRES) elements to recruit the translational machinery are poorly understood. In this study we show that protein-RNA interaction of the eIF4G translation initiation factor with sequences of the foot-and-mouth disease virus (FMDV) IRES is a key determinant of internal translation initiation in ...
S, López de Quinto, E, Martínez-Salas
openaire   +3 more sources

Spatial Patterns and Epidemiological Drivers of Foot‐and‐Mouth Disease Outbreaks in Uganda

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Foot‐and‐mouth disease (FMD) places a heavy economic burden on farmers and animal health authorities due to its clinical effects, the high cost associated with its prevention and control, and trade restrictions on livestock and livestock products in countries without FMD‐free recognition like Uganda.
Lina González Gordon, Dennis Muhanguzi, Adrian Muwonge, Sylvester Ochwo, Noelina Nantima, Rose Ademun, Lisa Boden, Norbert Frank Mwiine, Barend Mark de C. Bronsvoort, Thibaud Porphyre, Fedor Korennoy   +10 more
wiley   +1 more source

Foot-and-mouth disease in Asia

Virus Research
Foot-and-mouth disease (FMD) is a highly contagious transboundary disease prevalent across the Asian continent, affecting both wild and domestic artiodactyls.
Md. Abdur Rahman, Farah Zereen, Md. Liton Rana, Md. Golzar Hossain, Masaru Shimada, Sukumar Saha   +5 more
doaj   +1 more source

Identification of an essential region for internal initiation of translation in the aphthovirus internal ribosome entry site and implications for viral evolution [PDF]

Journal of Virology, 1996
Translation of aphthovirus RNA is initiated at an internal ribosome entry site (IRES) element, preceding the first functional AUG initiation codon. The effect of mutations at the base of domain 3 of the aphthovirus IRES on translation activity has been analyzed by site-directed mutagenesis and expression of bicistronic RNAs in transfected cells.
E, Martínez-Salas, M P, Regalado, E, Domingo   +2 more
openaire   +2 more sources

Prevalence and Serotype Distribution of Foot and Mouth Disease (FMD) Virus in Asian Countries: A Systematic Review and Meta‐Analysis

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Background Foot and mouth disease (FMD) is a highly contagious transboundary List A infectious disease of domesticated and wild cloven‐hoofed animals, causing considerable economic impact through production losses and trade bans on livestock. Objective This study aimed to determine the pooled prevalence of FMD and the distribution of FMD virus ...
Md Jisan Ahmed, Md Imran Hossain, Md Arifur Rahman, Md Ismile Hossain Bhuiyan, Prajwal Bhandari, Kazi Estieque Alam, Ritu Chalise, Israt Jahan Kaderi, Md Afiqul Islam Rahi, Tashmiah Tarin, Md Jahangir Alam, Ridwan Olamilekan Adesola, Delower Hossain, Mahmoud Elhaig   +13 more
wiley   +1 more source

Foot-and-Mouth Disease Virus Serotype A in Egypt

Emerging Infectious Diseases, 2007
We describe the characterization of a foot-and-mouth disease (FMD) serotype A virus responsible for recent outbreaks of disease in Egypt. Phylogenetic analysis of VP1 nucleotide sequences demonstrated a close relationship to recent FMD virus isolates ...
Nick J. Knowles, Jemma Wadsworth, Scott M. Reid, Katherine G. Swabey, Alaa A. El-Kholy, Adel Omar Abd El-Rahman, Hatem M. Soliman, Katja Ebert, Nigel P. Ferris, Geoffrey H. Hutchings, Robert J. Statham, Donald P. King, David J. Paton   +12 more
doaj   +1 more source

Cell Recognition by Foot-and-Mouth Disease Virus That Lacks the RGD Integrin-Binding Motif: Flexibility in Aphthovirus Receptor Usage [PDF]

Journal of Virology, 2000
ABSTRACT Cell surface molecules that can act as virus receptors may exert an important selective pressure on RNA viral quasispecies. Large population passages of foot-and-mouth disease virus (FMDV) in cell culture select for mutant viruses that render dispensable a highly conserved Arg-Gly-Asp (RGD) motif responsible for integrin
Baranowski, Eric, Ruiz-Jarabo, Carmen M., Sevilla, Noemi, Andreu, David, Beck, Ewald, Domingo, Esteban   +5 more
openaire   +4 more sources

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source

Glycosylated Foot‐And‐Mouth Disease Virus‐Like Particles Produced in Pichia Pastoris Enhance Stability and Immunogenicity

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
An N‐glycosylation was strategically introduced at the 166th position of VP1 via artificial mutagenesis. The glycans mainly consist of high‐mannose type, significantly enhancing the stability and uptake of VLPs. The glycosylated VLPs conferred a robust Th1‐type immune response in mice and pigs and provided 100% protection against FMDV in pigs ...
Zhiyao Li, Hu Dong, Shuanghui Yin, Manyuan Bai, Zhidong Teng, Lingbo Chen, Suyu Mu, Yun Zhang, Yaozhong Ding, Shiqi Sun, Huichen Guo   +10 more
wiley   +1 more source