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Foot and mouth disease virus vaccines

Vaccine, 2009
Foot and mouth disease (FMD) is a highly infectious and economically devastating disease of livestock. Although vaccines, available since the early 1900s, have been instrumental in eradicating FMD from parts of the world, the disease still affects millions of animals around the globe and remains the main sanitary barrier to the commerce of animals and ...
Luis L, Rodriguez, Marvin J, Grubman
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Cores in foot-and-mouth disease virus

Virology, 1982
Abstract Foot-and-mouth disease virions were dissociated with ammonium acetate and observed with the electron microscope. The major products of viral disassembly were 12 S viral subunits or skullcaps and cores. Cores appeared as spherical structures and were relatively unstable upon spreading, freezing and thawing, or treatment at low pH.
M S, Dubra   +4 more
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Molecular epidemiology of foot-and-mouth disease virus

Virus Research, 2003
Foot-and-mouth disease (FMD) is the most economically important veterinary pathogen due to its highly infectious nature, ability to cause persistent infections and long term effects on the condition and productivity of the many animal species it affects. Countries which have the disease have many trade restrictions placed upon them.
N J, Knowles, A R, Samuel
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Foot-and-mouth disease virus

Trends in Biochemical Sciences, 1981
Abstract Foot-and-mouth disease virus is the causative agent of the most economically important infectious disease of farm animals. The general features of its structure and mode of replication are known and the sequence of its RNA is being determined by the application of recombinant DNA technology.
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Structure of foot-and-mouth disease virus capsid

Virology, 1979
Abstract Electron microscope images of negative-stained particles of FMDV have been analyzed. The viral capsid appeared to be a pliant structure composed of monomers having an average width of about 2.5 nm and a length of 4 nm. Upon capsid disruption, a sequential and nonrandom detachment of skullcaps was observed.
C, Vasquez   +3 more
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Thermal stability of foot-and-mouth disease virus

Archives of Virology, 1981
The thermal stabilities of 146S component of seven strains of foot-and-mouth disease virus were found to differ considerably. Inactivation of infectivity with acetylethyleneimine (AEI) reduced the thermal stabilities of all but one of the viruses. Treatment of AEI inactivated and control virus preparations with glutaraldehyde stabilized 146S particles ...
T R, Doel, P J, Baccarini
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