Inactivation of foot and mouth disease virus for vaccine production
Inactivation is the loss by a virus of ability to reproduce and infect susceptible animals while retaining its antigenic properties. In this paper, the effectiveness of aminoethylethanolamine when used as an FMDV inactivant is shown.
D. V. Mikhalishin+3 more
doaj +1 more source
Construction of New Genetically Engineered Vaccine Strain for O-type Foot-and-Mouth Disease of Pig [PDF]
Foot-and-mouth disease is an acute and highly contagious viral infectious disease. Although the foot and mouthdisease vaccine has been applied in some parts of the world since the beginning of the 20th century, the currentepidemic of foot and mouth ...
Feifei, Liu
core +2 more sources
The impact of within-herd genetic variation upon inferred transmission trees for foot-and-mouth disease virus [PDF]
Full-genome sequences have been used to monitor the fine-scale dynamics of epidemics caused by RNA viruses. However, the ability of this approach to confidently reconstruct transmission trees is limited by the knowledge of the genetic diversity of ...
Haydon, Daniel+6 more
core +2 more sources
Dynamics of foot-and-mouth disease virus replication in cells at different phases of the cell-division cycle [PDF]
Foot-and-mouth-disease virus (FMDV) replicates in epithelial cells. The restriction of FMDV RNA to the basal cell layer of epithelia suggests a possible link between FMDV replication in vivo and the cell status.
Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN
doaj +1 more source
Thermostability of the foot-and-mouth disease virus capsid is modulated by lethal and viability-restoring compensatory amino acid substitutions [PDF]
Infection by viruses depends on a balance between capsid stability and dynamics. This study investigated biologically and biotechnologically relevant aspects of the relationship in foot-and-mouth disease virus (FMDV) between capsid structure and ...
Belsham, Graham J.+6 more
core +1 more source
Foot-and-Mouth Disease in the Middle East Caused by an A/ASIA/G-VII Virus Lineage, 2015–2016
Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015–2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent.
Katarzyna Bachanek-Bankowska+12 more
doaj +1 more source
Foot-and-Mouth Disease Impact on Smallholders - What Do We Know, What Don't We Know and How Can We Find Out More? [PDF]
Foot-and-mouth disease (FMD) endemic regions contain three-quarters of the world's FMD susceptible livestock and most of the world's poor livestock keepers. Yet FMD impact on smallholders in these regions is poorly understood.
Abao+80 more
core +1 more source
Virus-resistant pigs might help to stem next outbreak
By genetically engineering pigs to degrade a crucial viral protein, livestock can be made less susceptible to foot and mouth disease virus.
Lisbeth Ramirez-Carvajal+1 more
doaj +1 more source
Randomised field trial to evaluate serological response after foot-and-mouth disease vaccination in Turkey [PDF]
Despite years of biannual mass vaccination of cattle, foot-and-mouth disease (FMD) remains uncontrolled in Anatolian Turkey. To evaluate protection after mass vaccination we measured post-vaccination antibodies in a cohort of cattle (serotypes O, A and ...
Bulut, A N+6 more
core +1 more source
Molecular mechanisms of suppression of host innate immunity by foot-and-mouth disease virus
Foot-and-mouth disease (FMD) is an acute and highly contagious animal disease caused by foot-and-mouth disease virus (FMDV). The outbreaks of FMD have brought huge economic losses and the disease has been considered as one of the most harmful infectious ...
Kangli Li+4 more
doaj