Results 81 to 90 of about 95,707 (354)

A New EP300‐Related Syndrome With Prominent Developmental and Immune Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rubinstein Taybi syndrome (RTS) is a disorder of chromatin remodeling and transcriptional regulation caused by heterozygous pathogenic variants in CREBBP and EP300. RTS is characterized by a distinct facial gestalt, intellectual disability, structural kidney and heart differences, feeding difficulties, and broad thumbs and great toes ...
Devi Priyanka Maripuri, Jessica Gold, Nina Gold, Alanna Strong   +3 more
wiley   +1 more source

Seroprevalence and Molecular Detection of Foot and Mouth Disease Virus in Dairy Cattle Around Addis Ababa, Central Ethiopia

Veterinary Medicine: Research and Reports, 2021
Shazali Mohammed Awel,1,2 Getachew Mulatu Dilba,3 Bruk Abraha,2 Demeke Zewde,4 Bayeta Senbata Wakjira,4 Abde Aliy4 1Jigjiga University, College of Veterinary Medicine, Jigjiga, Ethiopia; 2Haramaya University, College of Veterinary Medicine, Dire Dawa ...
Awel SM, Dilba GM, Abraha B, Zewde D, Wakjira BS, Aliy A   +5 more
doaj  

Single-Cell Analysis of Foot-and-Mouth Disease Virus

Frontiers in Microbiology, 2020
With the rapid development of single-cell technologies, the mechanisms underlying viral infections and the interactions between hosts and viruses are starting to be explored at the single-cell level.
Hailong Wang, Hailong Wang, Xiu Xin, Congyi Zheng, Congyi Zheng, Chao Shen, Chao Shen   +6 more
doaj   +1 more source

Investigating intra-host and intra-herd sequence diversity of foot-and-mouth disease virus [PDF]

, 2016
Due to the poor-fidelity of the enzymes involved in RNA genome replication, foot-and-mouth disease (FMD) virus samples comprise of unique polymorphic populations.
Freimanis, Graham L., Haydon, Daniel T., King, David J., King, Donald P., Orton, Richard, Waters, Ryan A.   +5 more
core   +1 more source

Optogenetic control of transgene expression in Marchantia polymorpha

Applications in Plant Sciences, EarlyView.
Abstract Premise The model liverwort Marchantia polymorpha is an emerging testbed species for plant metabolic engineering but lacks well‐characterized inducible promoters, which are necessary to minimize biochemical and physiological disruption when over‐accumulating target products.
Anya Lillemor Lindström Battle, Lee James Sweetlove   +1 more
wiley   +1 more source

Network analysis and disease subnets for the SARS-CoV-2/Human interactome [PDF]

arXiv, 2020
Motivation: With the aim to amplify and make sense of interactions of virus-human proteins in the case of SARS-CoV-2, we performed a structural analysis of the network of protein interactions obtained from the integration of three sources: 1) proteins of virus SARS-CoV-2, 2)physical interactions between SARS-CoV-2 and human proteins, 3) known ...
arxiv  

Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus [PDF]

, 2016
The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cpro performs most of the proteolytic processing of the polyprotein expressed from the single open reading frame in
Curry, S, Leen, EN, Maree, FF, Yang, J
core   +4 more sources

Continuous purification of a parvovirus using two aqueous two‐phase extraction steps

Biotechnology Progress, EarlyView.
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold, Sheridan Waldack, Grace James, Trisha Colling, Lynn Manchester, Taravat Sarvari, Amanda Bekkala, Seth A. Kriz, Madison Baldwin, Emily Agustin‐Mazariegos, Michael J. Betenbaugh, Caryn L. Heldt   +11 more
wiley   +1 more source

Inactivation of foot and mouth disease virus for vaccine production

Ветеринария сегодня, 2023
Inactivation is the loss by a virus of ability to reproduce and infect susceptible animals while retaining its antigenic properties. In this paper, the effectiveness of aminoethylethanolamine when used as an FMDV inactivant is shown.
D. V. Mikhalishin, V. V. Mikhalishin, Y. М. Gochmuradov, Yu. S. El’kina   +3 more
doaj   +1 more source

Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction [PDF]

Viruses, MDPI, 2018, 11 (1), pp.15, 2019
Since the largest 2014-2016 Ebola virus disease outbreak in West Africa, understanding of Ebola virus infection has improved, notably the involvement of innate immune mediators. Amongst them, collectins are important players in the antiviral innate immune defense.
arxiv   +1 more source