Results 231 to 240 of about 67,237 (303)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Estimating the nationwide incidence of coxsackievirus A6-associated hand, foot and mouth disease in China, 2008-2022. [PDF]

Infect Dis Poverty
Liu Y, Wang N, Liu F, Li K, Ward MP, Grassly NC, Tu W, Yu J, Li W, Zhao Y, Zhang J, Dong J, Lu T, Liu M, Chang Z, Zhang Z.   +15 more
europepmc   +1 more source

Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse, Duncan Wilson, Hugo Morales Briceno, Pamela Garcia, Victor Zhang, Jessica Qiu, Tomas Kalincik, Neil Mahant, Victor Shue Chung Fung   +8 more
wiley   +1 more source

Genome-wide CRISPR screen identifies RNF24 as a critical host factor for foot-and-mouth disease virus entry. [PDF]

Front Cell Dev Biol
Zhang J, Liu H, Du J, Zhang M, Yin M, Zhao Q, Chen X, Li X, Lu Z, Xie S, Qian P.   +10 more
europepmc   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Functional Evaluation of Neutralizing Antibodies Against Foot-and-Mouth Disease Virus Serotype O Using a Luciferase-Based Surrogate Neutralization Assay. [PDF]

Viruses
Kim H, Kim DW, Chae Y, Kim Y, Cho G, Hwang JH, Lee YH, Park JH, Park SH.   +8 more
europepmc   +1 more source

Whole‐Brain Diffusion MRI at 7T With Universal Multiband GRAPE pTx Pulses

Magnetic Resonance in Medicine, EarlyView.
Purpose To improve signal strength and homogeneity of whole‐brain diffusion‐weighted imaging (DWI) at 7T. Methods Universal multiband excitation and refocusing pulses were optimized with the gradient ascent pulse engineering (GRAPE) algorithm across a database of B1+$$ {B}_1^{+} $$ and B0$$ {B}_0 $$ maps obtained from 20 subjects.
Marten Laufenberg, Daniel Löwen, Mónica Ferreira, Nicolas Boulant, Jennifer Faber, Tony Stöcker   +5 more
wiley   +1 more source

Epidemic Patterns of Foot and Mouth Disease in the Lao People's Democratic Republic. [PDF]

Transbound Emerg Dis
Petersen I, Young JR, Khounsy S, Phommachanh P, Christensen P, Theppangna W, Hughes T, Blacksell SD, Ward MP.   +8 more
europepmc   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Assessing the effects of limited vaccine supply on risk-based vaccination strategies in regions of endemic foot-and-mouth disease. [PDF]

Vet Res
Guyver-Fletcher G, Tildesley M.
europepmc   +1 more source