Results 31 to 40 of about 61,911 (310)

Estimation of seroconversion and vaccination impact against FMD in India during 2006–2022 using survey sampling and Bayesian approaches

Scientific Reports
In India, the eligible bovine population has been subjected to mandatory biannual Foot-and-mouth Disease (FMD) vaccination since 2004–05 and year-round serosurveillance to control FMD.
Samarendra Das, Bighneswar Barik, Saravanan Subramaniam, Jajati Keshari Mohapatra, Rabindra Prasad Singh   +4 more
doaj   +1 more source

Foot-and-mouth disease in elephants in Kerala state of India during 2013

Indian Journal of Animal Sciences, 2016
Foot-and-mouth disease (FMD) is a highly contagious acute vesicular disease of the cloven-hoofed animals including cattle, buffalo, sheep, goats, pigs along with more than 70 wildlife species.
MANORANJAN ROUT, NANDAKUMAR S. NAIR, BISWAJIT DAS, SARAVANAN SUBRAMANIAM, JAJATI KESHARI MOHAPATRA, BRAMHADEV PATTNAIK   +5 more
doaj   +1 more source

Profiling and functional analysis of differentially expressed circular RNAs identified in foot-and-mouth disease virus infected PK-15 cells

Veterinary Research, 2022
Circular RNAs (circRNAs) are a new type of endogenous noncoding RNA that exhibit a variety of biological functions. However, it is not clear whether they are involved in foot-and-mouth disease virus (FMDV) infection and host response.
JinKe Yang, Bo Yang, Yong Wang, Ting Zhang, Yu Hao, HuiMei Cui, DengShuai Zhao, XingGuo Yuan, XueHui Chen, ChaoChao Shen, WenQian Yan, HaiXue Zheng, KeShan Zhang, Xiangtao Liu   +13 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu   +19 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers. [PDF]

, 2014
We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon)
Forrest, S, Lear, Z, Ryan, M., Herod, M, Forrest, S., Ryan, M, Stonehouse, N.J., Rowlands, DJ, Herod, M.R., Stonehouse, NJ, Lear, Z., Rowlands, D.J.   +11 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Accuracy of models for the 2001 foot-and-mouth epidemic [PDF]

, 2008
Since 2001 models of the spread of foot-and-mouth disease, supported by the data from the UK epidemic, have been expounded as some of the best examples of problem-driven epidemic models.
Bessell, Paul R., Brooks, Stephen P., R. Deardon, P. R Bessell, M. J Tildesley, Savill, Nicholas J., N. J Savill, S. P Brooks, Keeling, Matthew James, M. E.J Woolhouse, Deardon, Rob, B. T Grenfell, Tildesley, Michael J., Keeling, Matt J., Woolhouse, Mark E. J., Grenfell, Bryan T., M. J Keeling, Woolhouse, Mark E. J.; id_orcid   +17 more
core   +1 more source

A comprehensive serosurveillance of foot-and-mouth disease in pig population of Mizoram state in eastern Himalayan agro-climatic region in India

Indian Journal of Animal Sciences
The primary objective of this study was to estimate the seroprevalence of foot-and-mouth disease virus (FMDV) 3AB3 nonstructural protein (NSP) antibodies in pig population of Mizoram.
MANORANJAN ROUT, ESTHER LALZOLIANI RALTE, CHHAKCHHUAK NEIHTHANGPUII, JAJATI KESHARI MOHAPATRA, SARAVANAN SUBRAMANIAM, RABINDRA PRASAD SINGH   +5 more
doaj   +1 more source