Results 61 to 70 of about 68,138 (259)

Control of foot-and-mouth disease [PDF]

, 2011
Livestock experiments provide precise parameters for incubation and infectious periods for foot-and-mouth disease virus.
Thrusfield, M., Adrian Wingfield, Sam Mansley, Kitching, P., Nick Taylor, Mansley, S., Paul Kitching, Taylor, Nick, Nick Honhold, Michael Thrusfield, Honhold, N., Wingfield, A., Hullinger, P., Pam Hullinger, Nicholas D. Juleff, Debi Gibson, Simon Gubbins, Paul V. Barnett, Bartlomies M. Bankowski, Mark E. J. Woolhouse, Margo E. Chase-Topping, David Schley, Bryan Charleston, Richard Howey   +23 more
core   +1 more source

Analysis of Amino Acid Mutations of the Foot-and-Mouth Disease Virus Serotype O Using both Heparan Sulfate and JMJD6 Receptors

Viruses, 2020
Foot-and-mouth disease (FMD) is an economically devastating animal disease. Adapting the field virus to cells is critical to the vaccine production of FMD viruses (FMDV), and heparan sulfate (HS) and Jumonji C-domain-containing protein 6 (JMJD6) are ...
Gyeongmin Lee, Ji-Hyeon Hwang, Aro Kim, Jong-Hyeon Park, Min Ja Lee, Byounghan Kim, Su-Mi Kim   +6 more
doaj   +1 more source

Validation of γ-radiation and ultraviolet as a new inactivators for foot and mouth disease virus in comparison with the traditional methods [PDF]

Veterinary World, 2015
Aim: The present work deals with different methods for foot and mouth disease virus (FMDV) inactivation for serotypes O/pan Asia, A/Iran05, and SAT-2/2012 by heat, gamma radiation, and ultraviolet (UV) in comparison with the traditional methods and their
Safy El din Mahdy, Amr Ismail Hassanin, Wael Mossad Gamal El-Din, Ehab El-Sayed Ibrahim, Hiam Mohamed Fakhry   +4 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

Advanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu, Xiao Xu, Fengming Hu, Yuanzhe Liang, Zidong Yin, Biao Qi, Ruolin Liu, Ziyi Dai, Jianyi Luo, Bingpu Zhou   +9 more
wiley   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Oral β-D-glucan potentiates systemic immune responses to intramuscular foot-and-mouth disease vaccination

Frontiers in Veterinary Science
BackgroundFoot-and-mouth disease (FMD) is a viral disease primarily affecting livestock. Although vaccination is the main strategy to control FMD, current commercial FMD vaccines have major drawbacks, such as low antibody titers and short antibody titer ...
Hyeong Won Kim, So Hui Park, Mi-Kyeong Ko, Seokwon Shin, Jong-Hyeon Park, Min Ja Lee   +5 more
doaj   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Use and abuse of mathematical models: an illustration from the 2001 foot and mouth disease epidemic in the United Kingdom [PDF]

, 2006
Foot and mouth disease (FMD) is a major threat, not only to countries whose economies rely on agricultural exports, but also to industrialised countries that maintain a healthy domestic livestock industry by eliminating major infectious diseases from ...
Thrusfield, M., Thrusfield, Michael, Kitching, R. P., Taylor, Nick M, Taylor, N. M., Kitching, Richard P   +5 more
core  

Bovine Genome-wide Association Study for Genetic Elements to Resist the Infection of Foot-and-mouth Disease in the Field [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
Foot-and-mouth disease (FMD) is a highly contagious disease affecting cloven-hoofed animals and causes severe economic loss and devastating effect on international trade of animal or animal products.
Bo-Young Lee, Kwang-Nyeong Lee, Taeheon Lee, Jong-Hyeon Park, Su-Mi Kim, Hyang-Sim Lee, Dong-Su Chung, Hang-Sub Shim, Hak-Kyo Lee, Heebal Kim   +9 more
doaj   +1 more source