Results 91 to 100 of about 2,704,426 (251)

Diabetic Calcaneal Osteomyelitis: Outcomes Before and After the Introduction of Bone Graft Substitutes—A Retrospective Cohort Study

Diabetology
Background: Calcaneal osteomyelitis is a severe form of diabetic foot osteomyelitis associated with poor healing, major amputation, and increased mortality. Evidence on the use of bone graft substitutes in this setting remains limited.
Roberto Da Ros, Enrica Barro, Andrea Michelli, Roberta Assaloni, Barbara Brunato, Marta Nardi, Cesare Miranda   +6 more
doaj   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

A chemiluminescence immunoassay for detecting neutralizing antibodies of foot-and-mouth disease virus serotype A

Applied Microbiology and Biotechnology
Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals, posing significant threats to global livestock industries.
Mengyang Sun, Yanfang Bao, Kun Li, Yili Zuo, Huiyan Zhang, Yuanfang Fu, Pinghua Li, Pu Sun, Zhixun Zhao, Tao Jiang, Xingwen Bai, Mi Lin, Zengjun Lu, Yimei Cao   +13 more
doaj   +1 more source

Effects of subtalar joint hypermobility on load-bearing capability of the musculoskeletal system of the foot during free gait- literature review

Advances in Rehabilitation, 2018
Flat foot is caused by subtalar joint hypermobility which leads to changes in foot mechanics while walking. It results in increased load of the musculoskeletal system of the foot.
Edyta Łukasik, Norbert Kapiński, Andrzej Mioduszewski, Michał Wychowański, Andrzej Wit   +4 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Molecular factors involved in the development of diabetic foot syndrome [PDF]

, 2012
Diabetes is one of the major challenges of modern medicine, as it is considered a global epidemic of the XXI century. The disease often leads to the development of serious, health threatening complications.
Brun-Olszewska, Bożena, Olszewski, Paweł, Węgrzyn, Alicja, Gabig-Cimińska, Magdalena, Korzon-Burakowska, Anna, Jakóbkiewicz-Banecka, Joanna   +5 more
core   +2 more sources

Remapping the spatial distribution of neutralizing sites and their immunodominance on the capsid of different topotypes of FMDV serotype O by site-directed competitive ELISA for detection of neutralizing antibodies

Microbiology Spectrum
The foot-and-mouth disease virus (FMDV) serotype O contains at least five neutralizing antigenic sites, yet the structural relationship and antibody abundance remain poorly characterized. This study identifies six distinct neutralizing antigenic sites by
Qiongqiong Zhao, Fengjuan Li, Shulun Huang, Xiangchuan Xing, Ying Sun, Pinghua Li, Huifang Bao, Yuanfang Fu, Pu Sun, Xingwen Bai, Hong Yuan, Xueqing Ma, Zhixun Zhao, Jing Zhang, Jian Wang, Tao Wang, Dong Li, Qiang Zhang, Ping Qian, Yimei Cao, Kun Li, Xiangmin Li, Zengjun Lu   +22 more
doaj   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Adipose Tissue Grafting: A New Paradigm in Diabetic Foot Treatment

Diabetology
Background: Adipose tissue grafting is a regenerative medicine approach based on the use of autologous adipose tissue showing significant potential for the treatment of diabetic foot lesions.
Roberto Da Ros, Roberta Assaloni, Andrea Michelli, Barbara Brunato, Enrica Barro, Marta Nardi, Giovanni Papa, Cesare Miranda   +7 more
doaj   +1 more source

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source