Results 71 to 80 of about 517,971 (261)

Final report on the farmer's aid in plant disease diagnoses [PDF]

open access: yes, 1986
This report is the final report on the FAD project. The FAD project was initiated in september 1985 to test the expert system shell Babylon by developing a prototype crop disease diagnosis system in it.
Curwiel, P.H., Wieringa, R.J.
core   +3 more sources

Correlation of Adherence to the 2012 Infectious Diseases Society of America Practice Guidelines with Patient Outcomes in the Treatment of Diabetic Foot Infections in an Outpatient Parenteral Antimicrobial Programme [PDF]

open access: yes, 2014
Aim To evaluate adherence to the 2012 Infectious Diseases Society of America practice guidelines for the management of patients with diabetic foot infections and to determine an association between adherence and clinical outcome.
Damer, Kendra M.   +5 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Organic Livestock: Animal Health, Welfare and Husbandry Assessment of existing knowledge and production of an advisory resource compendium(OF0162) [PDF]

open access: yes, 2001
1. A compendium of animal health and welfare information relevant to organic livestock production has been produced by the Organic Livestock Research Group (OLRG), Veterinary Epidemiology and Economics Research Unit (VEERU), Department of Agriculture ...
Hovi, Malla, Roderick, Stephen
core  

Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]

open access: yes, 2014
Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony   +10 more
core   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Aspects of bovine caesarean section associated with calf mortality, dam survival and subsequent fertility.

open access: yes, 2013
Bovine caesarean section is a common surgery performed by cattle practitioners yet evidence for justifying many aspects of the surgical procedure is lacking.
Karvountzis, S   +2 more
core   +1 more source

A New Decision Support Framework for Managing Foot-and-mouth Disease Epidemics [PDF]

open access: yes, 2014
Animal disease epidemics such as the foot-and-mouth disease (FMD) pose recurrent threat to countries with intensive livestock production. Efficient FMD control is crucial in limiting the damage of FMD epidemics and securing food production.
Ge, L.   +3 more
core   +2 more sources

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