Results 111 to 120 of about 9,817,386 (374)

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan   +8 more
wiley   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

Features of revascularization of the lower extremity in patients with diabetic foot

open access: yesКлінічна та профілактична медицина, 2020
Objective: To determine specific features of peripheral arterial diseases in patients with diabetic foot that influence the choice of revascularization method. Introduction.
D. Shapovalov   +5 more
doaj   +1 more source

Foot Conditions among Homeless Persons: A Systematic Review

open access: yesPLoS ONE, 2016
Introduction Foot problems are common among homeless persons, but are often overlooked. The objectives of this systematic review are to summarize what is known about foot conditions and associated interventions among homeless persons.
Matthew J To, T. Brothers, C. Van Zoost
semanticscholar   +1 more source

Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos   +11 more
wiley   +1 more source

Effects of subtalar joint hypermobility on load-bearing capability of the musculoskeletal system of the foot during free gait- literature review

open access: yesAdvances in Rehabilitation, 2018
Flat foot is caused by subtalar joint hypermobility which leads to changes in foot mechanics while walking. It results in increased load of the musculoskeletal system of the foot.
Edyta Łukasik   +4 more
doaj   +1 more source

“Pre-columbian moulages”. Huacos, mummies and photographs in the controversy over precolumbian diseases, 1894-1910 [PDF]

open access: yes, 2015
By the late nineteenth century an international controversy arose referred to the probable existence of certain diseases such as leprosy, syphilis and lupus in pre-Columbian America.
Farro, Máximo Ezequiel, Podgorny, Irina
core   +1 more source

A New Decision Support Framework for Managing Foot-and-mouth Disease Epidemics [PDF]

open access: yes, 2014
Animal disease epidemics such as the foot-and-mouth disease (FMD) pose recurrent threat to countries with intensive livestock production. Efficient FMD control is crucial in limiting the damage of FMD epidemics and securing food production.
Ge, L.   +3 more
core   +2 more sources

Uses of Braces and Orthotics for Conservative Management of Foot and Ankle Disorders

open access: yesFoot & Ankle Orthopaedics, 2018
Nonsurgical management is almost always considered the first-line treatment for the vast majority of foot and ankle pathologies. Foot orthoses, shoe modifications, and therapeutic footwear are considered essential tools for successful conservative ...
Osama Elattar   +4 more
semanticscholar   +1 more source

Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee   +26 more
wiley   +1 more source

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