Results 51 to 60 of about 194,478 (312)

Bone Substitute in Diabetic Foot Osteomyelitis Treatment

open access: yesDiabetology
Background: Diabetic foot osteomyelitis (DFO) constitutes a severe and prevalent complication of diabetes mellitus (DM). Individuals afflicted with DM exhibit an elevated risk for DFO development, attributable to a confluence of factors, including ...
Roberto Da Ros   +5 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Impact of ankylosing spondylitis on foot health and quality of life: an observational case–control study

open access: yesFrontiers in Medicine
BackgroundAnkylosing spondylitis (AS) is a chronic, inflammatory, and autoimmune disease. This condition primarily affects the axial skeleton and presents direct foot involvement, such as Achilles enthesitis or plantar fascia involvement.ObjectiveThis ...
Antonio Cortes-Rodríguez   +10 more
doaj   +1 more source

Corrigendum: Bilateral plantar deep cleft

open access: yesThe Pan African Medical Journal, 2018
This corrigendum corrects article ''Bilateral plantar deep cleft'' and its publication references ie The Pan African Medical Journal. 2017;28:312. doi:10.11604/pamj.2017.28.312.14502.
Fred Bernardes Filho
doaj   +1 more source

Efficacy Evaluation of Ciprofloxacin-Loaded Poly (Trimethylene Carbonate) Implants in the Treatment of Chronic Osteomyelitis

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
In this study, poly (trimethylene carbonate) (PTMC) with excellent biocompatibility was synthesized via ring-opening of TMC to prepare the Ciprofloxacin-loaded PTMC implants, and antibacterial effects in vitro or in vivo of the resulting implants were ...
Yixiu Liu   +7 more
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

An Epidemic Model on Small-World Networks and Ring Vaccination [PDF]

open access: yes, 2001
A modified version of susceptible-infected-recovered-susceptible (SIRS) model for the outbreaks of foot-and-mouth disease (FMD) is introduced. The model is defined on small-world networks, and a ring vaccination programme is included. This model can be a theoretical explanation for the nonlocal interactions in epidemic spreading.
arxiv   +1 more source

Dynamics for a two phases free boundaries system in an epidemiological model with nonlocal dispersals [PDF]

open access: yesarXiv, 2021
The present paper is devoted to the investigation of the long time dynamics for a double free boundary system with nonlocal diffusions, which models the infectious diseases transmitted via digestive system such as fecal-oral diseases, cholera, hand-foot and mouth, etc...We start by proving the existence and uniqueness of the Cauchy problem, which is ...
arxiv  

Molecular Infectious Disease Epidemiology: Survival Analysis and Algorithms Linking Phylogenies to Transmission Trees [PDF]

open access: yesPLoS Computational Biology 12(4): e1004869, April 2016, 2015
Recent work has attempted to use whole-genome sequence data from pathogens to reconstruct the transmission trees linking infectors and infectees in outbreaks. However, transmission trees from one outbreak do not generalize to future outbreaks. Reconstruction of transmission trees is most useful to public health if it leads to generalizable scientific ...
arxiv   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

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