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Charcot neuroarthropathy is a progressive condition characterized by joint dislocations, pathological fractures and debilitating deformities. This pathology occurs most commonly in the joints of the foot and ankle.
Ravnik Singh, DPM +1 more
doaj +1 more source
The effectiveness of salicylic acid plasters compared with 'usual' scalpel debridement of corns: a randomised controlled trial [PDF]
Background Corns are a common foot problem and surveys have indicated that between 14-48% of people suffer from them. Many of these will seek podiatry treatment, however there is little evidence to indicate which current treatments provide long term ...
Dixon, S. +20 more
core +2 more sources
Neuropathy - gait changes in the diabetic foot [PDF]
Motor neuropathy in patients with diabetes can lead to weakness in the muscles of the foot and lower leg, which in turn can lead to characteristic changes to the structure of the foot, such as an altered arch profile.
McIntosh, Caroline, Newton, Veronica
core +3 more sources
Disease knowledge in patients attending a diabetic foot clinic
Background: Foot-specific patient education is an essential element of a health system diabetic foot program. Foot-specific patient education must be individualized, because of cognitive deficits in individuals with long-standing diabetes.
Batista, Fabio [UNIFESP] +3 more
core +1 more source
A sock for foot-drop: A preliminary study on two chronic stroke patients [PDF]
Background: Foot-drop is a common motor impairment of chronic stroke patients, which may be addressed with an ankle foot orthosis. Although there is reasonable evidence of effectiveness for ankle foot orthoses, user compliance is sometimes poor.
Cooper, G. +9 more
core +1 more source
Distal tibia giant cell tumor surgical treatment: A case report
Giant Cell Tumor is a very common benign bone tumor occurring in young adults 20-40’s which has an unpredictable behavior. It is locally aggressive with a chance to infiltrate soft tissue and metastasize.
Ralph Napoli, DPM, FACAFS +2 more
doaj +1 more source
Background: For hallux rigidus, dorsal cheilectomy remains a treatment option even with advances in interposition techniques and devices. Cheilectomy aims to alleviate dorsal impingement and improve pain and function as well as range of motion ...
Sara Heintzman Galli MD +7 more
doaj +1 more source
Surgical Management of Diabetic Foot Ulcers: A Tanzanian University Teaching Hospital Experience. [PDF]
\ud \ud Diabetic foot ulcers (DFUs) pose a therapeutic challenge to surgeons, especially in developing countries where health care resources are limited and the vast majority of patients present to health facilities late with advanced foot ulcers.
Kabangila Rodrick +35 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

