Results 61 to 70 of about 12,243,471 (240)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Footwear and Foot Health: Unveiling the Role of Proper Shoe Fit in Preventing Podiatric Issues and Enhancing Well-Being

Applied Sciences
Background: The appropriate choice of footwear is crucial for foot health, yet its impact on different populations and medical conditions remains understudied.
Roberto Tedeschi, Federica Giorgi, Danilo Donati   +2 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Provision of foot and ankle care services for people with rheumatic and musculoskeletal disease across Europe [PDF]

, 2020
Background: The aim of the present study was to explore the variation in theprovision of care for people with rheumatic and musculoskeletal diseases (RMDs),and foot and ankle problems between European healthcare systems.Methods: An electronic ...
Ferreira, Andre, Redmond, Anthony C., Alfred Gatt, Michael Ross Backhouse, Backhouse, MR, Tiziana Nava, Bonafede, Sofia, Gatt, Alfred, Backhouse, Michael, Alcacer-Pitarch, Begonya, Backhouse, Michael Ross, Nava, Tiziana, Gijon-Nogeron, Gabriel, EULAR Foot & Ankle Study Group, Anthony C. Redmond, Gijon‐Nogeron, G, Yves Lescure, Gatt, A, Redmond, AC, Alcacer‐Pitarch, B, Ferreira, A, Andre Ferreira, Biscontini, Devid, Sofia Bonafede, Bonafede, S, Devid Biscontini, Gijon‐Nogeron, Gabriel, Nava, T, Alcacer‐Pitarch, Begonya, Biscontini, D, Begonya Alcacer‐Pitarch, Lescure, Yves, Lescure, Y, Gabriel Gijon‐Nogeron   +33 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Development of a practical guide for the early recognition for malignant melanoma of the foot and nail unit [PDF]

, 2010
Background: malignant melanoma is a rare but potentially lethal form of cancer which may arise on the foot. Evidence suggests that due to misdiagnosis and later recognition, foot melanoma has a poorer prognosis than cutaneous melanoma elsewhere.Methods ...
David AR de Berker, de Berker, David, Ivan R Bristow, de Berker David AR, Bristow, Ivan R., Bristow Ivan R   +5 more
core   +2 more sources

Comparative Analysis of Foot Arch Index between Yogic and Non-Yogic Female Practitioners

Anthropological Review
Introduction With advancing age in females, gait patterns change due to several factors, including nutritional and hormonal influences. These changes can lead to a lowering of the foot arch, resulting in mild valgus and varus deformities.
Saurabh Mishra, Binayak Kumar Dubey, Bhuwan Chandra Kapri   +2 more
doaj   +1 more source

Distal tibial distraction osteogenesis—an alternative approach to addressing limb length discrepancy with concurrent hindfoot and ankle reconstruction

Journal of Orthopaedic Surgery and Research, 2019
Background Limb length discrepancy (LLD) in the setting of concurrent hindfoot and ankle deformity poses an added level of complexity to the reconstructive surgeon.
Todd M. Chappell, Casey C. Ebert, Kevin M. McCann, Byron L. Hutchinson, Edgardo Rodriguez-Collazo   +4 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source